{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:59:10Z","timestamp":1785499150196,"version":"3.56.0"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post\u2010intensive care syndrome includes physical, cognitive and psychological impairments that may persist after discharge from the intensive care unit (ICU), with anxiety and depression among the most commonly reported symptoms. Evidence on these symptoms beyond the first year after discharge remains limited, particularly in patients admitted for COVID\u201019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To determine the prevalence and characteristics of anxiety and depression symptoms among patients previously admitted to the ICU for COVID\u201019 within three years after discharge, and to examine differences according to sociodemographic and clinical variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>A multicentre, descriptive cross\u2010sectional study was conducted among ICU survivors in Spain using clinical records and structured telephone interviews. Sociodemographic, clinical and patient\u2010reported outcomes were obtained. The Hospital Anxiety and Depression Scale (HADS) was used to assess symptoms of anxiety (HADS\u2010A) and depression (HADS\u2010D).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 106 participants were included. Mean anxiety (HADS\u2010A) and depression (HADS\u2010D) scores were 6.5 (SD \u00b13.9) and 6.7 (SD \u00b13.8), respectively. Female sex was linked to higher anxiety (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20091.73; 95% CI, 0.32\u20133.13;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016), while memory problems were associated with higher anxiety (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20091.49; 95% CI, 0.14\u20132.83;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031) and depression (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20091.65; 95% CI, 0.43\u20132.86;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009). Depression was also higher in participants with greater pain (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.50; 95% CI, 0.15\u20130.84;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006). Higher quality of life (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.07; 95% CI, \u22120.11 to \u22120.03;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) was associated with lower depression scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Anxiety and depression were common among individuals with a history of ICU admission due to COVID\u201019 up to three years after discharge. Psychological symptoms should be considered alongside physical and cognitive aspects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance to Clinical Practice<\/jats:title>\n                    <jats:p>Incorporating psychological assessment into the long\u2010term follow\u2010up may facilitate identifying individuals who may benefit from further support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nicc.70577","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:44:31Z","timestamp":1783676671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anxiety and Depression Symptoms in ICU Survivors After COVID\u201019"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5623-2930","authenticated-orcid":false,"given":"Cristina","family":"Sanchez\u2010Lorenzo","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Central University Hospital of Asturias  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0703-7849","authenticated-orcid":false,"given":"Aida","family":"G\u00e1mez\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"University of Oviedo  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8379-5395","authenticated-orcid":false,"given":"Marta","family":"S\u00e1nchez\u2010Zaballos","sequence":"additional","affiliation":[{"name":"University of Oviedo  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3375-9334","authenticated-orcid":false,"given":"Maria\u2010Pilar","family":"Mosteiro\u2010Diaz","sequence":"additional","affiliation":[{"name":"University of Oviedo  Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.enfcle.2022.07.003","article-title":"Scales to Measure Post Intensive Care Syndrome, a Scoping Review","volume":"32","author":"Narv\u00e1ez\u2010Mart\u00ednez M. A.","year":"2022","journal-title":"Enfermer\u00eda Cl\u00ednica [Internet]"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2022.09.013"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.5114\/ait.2023.130831"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318232da75"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000525"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare10091716"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2024.05.002"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/20008066.2024.2363654"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202009-3381OC"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medine.2024.01.008"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182111049"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2023.01.005"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.2340\/jrm.v56.40654"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aucc.2022.01.002"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnsa.2025.100429"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054\u2010019\u20102678\u20100"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010011\u20109903\u2010x"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2017.10.023"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(76)90113-5"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100447.1983.tb09716.x"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0163\u20108343(03)00043\u20104"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/17511437241312113"},{"key":"e_1_2_15_24_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2025"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_15_26_1","volume-title":"Regulation (EU) 2016\/679 of the European Parliament and of the Council of 27 April 2016 on the Protection of Natural Persons With Regard to the Processing of Personal Data and on the Free Movement of Such Data (General Data Protection Regulation) [Internet]","author":"European Parliament and Council of the European Union","year":"2016"},{"key":"e_1_2_15_27_1","volume-title":"Organic Law 3\/2018 of 5 December on the Protection of Personal Data and Guarantee of Digital Rights [Internet]","author":"Government of Spain","year":"2018"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888\u2010024\u201005603\u20108"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.15649\/cuidarte.3998"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.5812\/apid-149370"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.4236\/psych.2022.1312111"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40560\u2010025\u201000812\u2010z"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054\u2010024\u201004989\u2010x"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.2024.v114i17.1988"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2024.111602"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci12070939"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40560\u2010023\u201000670\u20107"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2022.09.035"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1236990"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1288761"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/17511437241308674"}],"container-title":["Nursing in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nicc.70577","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nicc.70577","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nicc.70577","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:19:48Z","timestamp":1785496788000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nicc.70577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/nicc.70577"],"URL":"https:\/\/doi.org\/10.1111\/nicc.70577","archive":["Portico"],"relation":{},"ISSN":["1362-1017","1478-5153"],"issn-type":[{"value":"1362-1017","type":"print"},{"value":"1478-5153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2025-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70577"}}