{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:00:36Z","timestamp":1790060436475,"version":"4.0.1"},"reference-count":95,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing in Critical Care"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Critical illness threatens the Quality of Life (QoL) of both ICU survivors and their family members through Post\u2010Intensive Care Syndrome (PICS) and its family counterpart (PICS\u2010F). These syndromes unfold within the ICU survivor\u2013family member dyad, yet their dyadic interdependence and joint trajectories remain insufficiently explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To develop a conceptual framework and study protocol for a longitudinal investigation of dyadic QoL in ICU survivor\u2013family member dyads, with explicit attention to reciprocal interdependence over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and Methods<\/jats:title>\n                    <jats:p>\n                      A longitudinal study will enrol ICU survivor\u2013family member dyads assessed at 1, 3, 6 and 12\u2009months post\u2010ICU discharge in two Italian ICUs. The 1\u2010month timepoint captures early PICS and PICS\u2010F manifestations while minimising post\u2010discharge confounding. A qualitative phenomenological component will explore how survivorship is experienced within the dyad. Dyadic QoL trajectories will be examined using descriptive statistics,\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      tests, Student's\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests and Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      \u2010tests. Longitudinal analyses will apply hierarchical linear models to capture trajectories over time. Qualitative data will be analysed manually following Cohen's hermeneutic phenomenological approach.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This protocol advances the conceptualisation of post\u2010ICU outcomes as dyadic and interdependent, integrating quantitative and qualitative evidence within a relational framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance to Clinical Practice<\/jats:title>\n                    <jats:p>Findings will inform nurse\u2010led follow\u2010up interventions targeting ICU survivors and family members as an interdependent unit, supporting person\u2010 and family\u2010centred care across the post\u2010ICU trajectory.<\/jats:p>\n                  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