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This paper aims to describe the influences of transhumanist perspectives on human\u2010technology enhancements and replacements in the transcendence of human frailties, including those of older persons, in which technology is projected to deliver solutions toward transcending these frailties. Through technologies including genetic screening and other technological manipulations, intelligent machines and augmented humans improve, maintain, and remedy human\u2010linked susceptibilities. Furthermore, other technologies replace parts fabricated through inorganic\u2010mechanical processes such as 3D\u2010printing. Advancing technologies are reaching the summit of technological sophistication contributing to the transhumanist views of being human in a technological world. Technologies enhance the transcendence of human frailties as essential expressions of the symbiosis between human beings and technology in a transcendental world.<\/jats:p>","DOI":"10.1111\/nin.12391","type":"journal-article","created":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T19:04:38Z","timestamp":1604775878000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transcending human frailties with technological enhancements and replacements: Transhumanist perspective in nursing and healthcare"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2952-6538","authenticated-orcid":false,"given":"Rozzano C.","family":"Locsin","sequence":"first","affiliation":[{"name":"Department of Nursing Faculty of Nursing Chiang Mai University Chiang Mai Thailand"},{"name":"Tokushima University Graduate School of Biomedical Sciences Tokushima Japan"},{"name":"Florida Atlantic University Christine E. Lynn College of Nursing Boca Raton FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph Andrew","family":"Pepito","sequence":"additional","affiliation":[{"name":"College of Allied Medical Sciences Cebu Doctors\u2019 University Cebu City Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phanida","family":"Juntasopeepun","sequence":"additional","affiliation":[{"name":"Department of Policy, Planning, and IT Management Faculty of Nursing Chiang Mai University Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rose E.","family":"Constantino","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Nursing Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12304\u2010017\u20109286\u20107"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5340616"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/EMPH"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/philosophies4010010"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/philosophies2010004"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.20517\/jtgg.2018.17"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/02642069.2019.1672666"},{"key":"e_1_2_9_9_1","volume-title":"Race after technology: Abolitionist tools for the new Jim code","author":"Benjamin R.","year":"2019"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/02763869.2012.670604"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.9.JNS141001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/iju.IJU_74_19"},{"issue":"1","key":"e_1_2_9_13_1","first-page":"1","article-title":"A history of transhumanist thought","volume":"14","author":"Bostrom N.","year":"2005","journal-title":"Journal of Evolution and Technology"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/1369823042000235967"},{"key":"e_1_2_9_15_1","volume-title":"Nursing as caring: A model for transforming practice","author":"Boykin A.","year":"2001"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11042\u2010019\u201008348\u20109"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059\u2010019\u20101626\u20102"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/scirobotics.aan4831"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2018.02086"},{"key":"e_1_2_9_20_1","volume-title":"Transhumanism: Meet the cyborgs and biohackers redefining beauty","author":"CNN","year":"2020"},{"key":"e_1_2_9_21_1","first-page":"213","volume-title":"Diversity across disciplines: Research on people, policy, process, and paradigm","author":"Constantino R. 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