{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:09Z","timestamp":1772160789096,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,22]],"date-time":"2013-04-22T00:00:00Z","timestamp":1366588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We previously showed that abdominal distension in patients with functional gut disorders is due to a paradoxical diaphragmatic contraction without major increment in intraabdominal volume. Our aim was to characterize the pattern of gas retention and the abdomino\u2010thoracic mechanics associated with abdominal distension in patients with intestinal dysmotility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In 15 patients with manometrically proven intestinal dysmotility, two abdominal\n                      <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                      scans were performed: one during basal conditions and other during an episode of severe abdominal distension. In 15 gender\u2010 and age\u2010matched healthy controls, a basal scan was performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>In basal conditions, patients exhibited more abdominal gas than healthy subjects, particularly in the small bowel, and the volume significantly increased during an episode of distension. During episodes of abdominal distension, the increase in abdominal content was associated with increased girth and antero\u2010posterior abdominal diameter, as well as a cephalic displacement of the diaphragm, which reduced the height of the lung. The consequent reduction in the air volume of the lung was attenuated by an increase in the antero\u2010posterior diameter of the chest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions &amp; Inferences<\/jats:title>\n                    <jats:p>Abdominal distension in patients with severe intestinal dysfunction is related to marked pooling of gut contents, particularly in the small bowel. This increase in content is accommodated within the abdominal cavity by a global and coordinated abdomino\u2010phreno\u2010thoracic response, involving an accommodative ascent of the diaphragm and a compensatory expansion of the chest wall.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.12128","type":"journal-article","created":{"date-parts":[[2013,4,23]],"date-time":"2013-04-23T03:46:23Z","timestamp":1366688783000},"source":"Crossref","is-referenced-by-count":26,"title":["Mechanisms of abdominal distension in severe intestinal dysmotility: abdomino\u2010thoracic response to gut retention"],"prefix":"10.1111","volume":"25","author":[{"given":"E.","family":"Barba","sequence":"first","affiliation":[{"name":"Digestive System Research Unit University Hospital Vall d'Hebron Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (Ciberehd) Barcelona Spain"},{"name":"Departament de Medicina Universitat Aut\u00f2noma de Barcelona Bellaterra (Cerdanyola del Vall\u00e8s) Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Quiroga","sequence":"additional","affiliation":[{"name":"Radiology Department University Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Accarino","sequence":"additional","affiliation":[{"name":"Digestive System Research Unit University Hospital Vall d'Hebron Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (Ciberehd) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. M.","family":"Lahoya","sequence":"additional","affiliation":[{"name":"Department of Computer Languages and System Universidad Polit\u00e9cnica de Catalu\u00f1a Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Malagelada","sequence":"additional","affiliation":[{"name":"Digestive System Research Unit University Hospital Vall d'Hebron Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (Ciberehd) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Burri","sequence":"additional","affiliation":[{"name":"Digestive System Research Unit University Hospital Vall d'Hebron Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (Ciberehd) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Navazo","sequence":"additional","affiliation":[{"name":"Department of Computer Languages and System Universidad Polit\u00e9cnica de Catalu\u00f1a Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. \u2010R.","family":"Malagelada","sequence":"additional","affiliation":[{"name":"Digestive System Research Unit University Hospital Vall d'Hebron Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (Ciberehd) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Azpiroz","sequence":"additional","affiliation":[{"name":"Digestive System Research Unit University Hospital Vall d'Hebron Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (Ciberehd) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.12.036"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.02141.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.408"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01846.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.01.067"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.28.1.5"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.084"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.17.s1.7.x"},{"key":"e_1_2_10_10_1","first-page":"391","volume-title":"Progress in Pain Research and Management","author":"Azpiroz F.","year":"1995"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01071.x"},{"key":"e_1_2_10_12_1","volume-title":"The ITK Software Guide","author":"Iba\u00f1ez L","year":"2003"},{"key":"e_1_2_10_13_1","volume-title":"The Visualization Toolkit, an Object Oriented Approach to 3D Graphics","author":"Schroeder W","year":"2002"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2007.00902.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-6189-2.00016-0"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01447.x"}],"container-title":["Neurogastroenterology &amp; Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnmo.12128","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.12128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T05:36:03Z","timestamp":1698644163000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.12128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,22]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1111\/nmo.12128"],"URL":"https:\/\/doi.org\/10.1111\/nmo.12128","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718019899.793478556","asserted-by":"object"}]},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"value":"1350-1925","type":"print"},{"value":"1365-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,22]]}}}