{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T13:42:37Z","timestamp":1782826957911,"version":"3.54.5"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,5,27]],"date-time":"2013-05-27T00:00:00Z","timestamp":1369612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Abdominal pain is common in patients with functional bowel disorders (<jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content>s). The aim of this study was to characterize the predominant sites of abdominal pain associated with <jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content> subtypes, as defined by the Rome <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 584 consecutive patients attending <jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content> consultations in a tertiary center participated in the study. Stool form, abdominal pain location (nine abdominal segments), and pain intensity (10\u2010point Likert scale) during the previous week were recorded. Logistic regression analysis was used to characterize the association of abdominal pain sites with specific <jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content> subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content>s were associated with predominant pain sites. Irritable bowel syndrome (<jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content>) with constipation was associated with pain in the left flank and patients were less likely to report pain in the right hypochondrium. Patients with functional constipation reported pain in the right hypochondrium and were less likely to report pain in the left flank and left iliac site. <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> with alternating constipation and diarrhea was associated with pain in the right flank, and unsubtyped <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> with pain in the hypogastrium Patients with functional abdominal pain syndrome reported the lower right flank as predominant pain site. Patients with unspecified <jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content>s were least likely to report pain in the hypogastrium.<\/jats:p><jats:p>Patients with functional diarrhea, <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> with diarrhea, or functional bloating did not report specific pain sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>The results from this study provide the basis for developing new criteria allowing for the identification of homogeneous groups of patients with non\u2010diarrheic <jats:styled-content style=\"fixed-case\">FBD<\/jats:styled-content>s based on characteristic sites of pain.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12149","type":"journal-article","created":{"date-parts":[[2013,5,27]],"date-time":"2013-05-27T07:30:51Z","timestamp":1369639851000},"page":"686","source":"Crossref","is-referenced-by-count":10,"title":["Abdominal pain localization is associated 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