{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:31:05Z","timestamp":1790947865796,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,8,14]],"date-time":"2013-08-14T00:00:00Z","timestamp":1376438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Few studies have investigated the biomechanical changes in the upper esophageal sphincter (<jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content>) and pharyngeal function after successful dilatation therapy for dysphagia. Using high\u2010resolution manometry (<jats:styled-content style=\"fixed-case\">HRM<\/jats:styled-content>), we examined the biomechanical properties of swallowing in brainstem stroke patients with dysphagia following modified balloon dilation therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>30 brainstem stroke patients with dysphagia were included. Patients in the experimental group received 3\u00a0weeks of modified balloon dilatation treatment and regular dysphagia therapy. Patients in the control group received 3\u00a0weeks of regular dysphagia therapy only. Efficacy of treatment was evaluated before and following intervention. Functional oral intake was measured using the Functional Oral Intake Scale (<jats:styled-content style=\"fixed-case\">FOIS<\/jats:styled-content>). Pharyngeal maximum pressures and duration, <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> residual pressure and duration during swallowing were measured using <jats:styled-content style=\"fixed-case\">HRM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>In the experimental group, the feeding tube was able to be removed in 12 of 15 patients, <jats:italic>vs<\/jats:italic> 2 of 15 patients in the control group. The experimental group had 4\u2010point median improvement, while control groups only had 1\u2010point improvement in <jats:styled-content style=\"fixed-case\">FOIS<\/jats:styled-content> scores. In the experimental group, posttreatment <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> relaxation and pharyngeal propulsion were both significantly improved for the three materials (p\u00a0&lt;\u00a00.05) and <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> resting pressure approximated normal. In the control group, pharyngeal propulsion was improved for water and thick liquids (p\u00a0&lt;\u00a00.05) but not for paste material; there was no improvement in posttreatment <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> relaxation for all three materials (p\u00a0&gt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>Dysphagia therapy with modified dilatation improved <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> relaxation, strengthened pharyngeal propulsion, restored <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> resting pressure and improved functional oral intake to a greater extent than regular therapy alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12209","type":"journal-article","created":{"date-parts":[[2013,8,14]],"date-time":"2013-08-14T10:13:39Z","timestamp":1376475219000},"source":"Crossref","is-referenced-by-count":37,"title":["Biomechanical changes in the pharynx and upper esophageal sphincter after modified balloon dilatation in brainstem stroke patients with dysphagia"],"prefix":"10.1111","volume":"25","author":[{"given":"Y.","family":"Lan","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine The Third Affiliated Hospital Sun Yat\u2010sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine The First Affiliated Hospital Sun Yat\u2010sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Dou","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine The Third Affiliated Hospital Sun Yat\u2010sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of 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