{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T14:07:22Z","timestamp":1780754842622,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T00:00:00Z","timestamp":1438214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Medspira Inc"},{"name":"National Institute of Health","award":["RO1 DK 78924"],"award-info":[{"award-number":["RO1 DK 78924"]}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences (NCATS)","doi-asserted-by":"crossref","award":["UL1 TR000135"],"award-info":[{"award-number":["UL1 TR000135"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2015,10]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Currently, anorectal manometry (ARM<\/jats:styled-content>), which is used to diagnose defecatory disorders and identify anal weakness in fecal incontinence (FI<\/jats:styled-content>) is generally conducted in specialized laboratories. Our aims were to compare anorectal functions measured with high\u2010resolution manometry (HRM<\/jats:styled-content>) and a novel portable manometry device.<\/jats:p><\/jats:sec>Methods<\/jats:title>Anal pressures at rest, during squeeze, and simulated evacuation, and rectal sensation were evaluated with portable and HRM<\/jats:styled-content> in 20 healthy women, 19 women with constipation, and 11 with FI<\/jats:styled-content>. The relationship between anal pressures measured with portable and HRM<\/jats:styled-content> was assessed by the concordance correlation coefficient (CCC<\/jats:styled-content>), Bland Altman test, and paired t<\/jats:italic>\u2010tests.<\/jats:p><\/jats:sec>Key Results<\/jats:title>Anal pressures at rest (CCC<\/jats:styled-content> 0.45; 95% CI<\/jats:styled-content>: 0.29, 0.58) and during squeeze (CCC<\/jats:styled-content> 0.60; 95% CI<\/jats:styled-content>: 0.46, 0.72) measured with portable and HRM<\/jats:styled-content> were correlated and inversely associated with the risk of FI<\/jats:styled-content>. During simulated evacuation, the CCC<\/jats:styled-content> for rectal pressure (0.62; 95% CI<\/jats:styled-content>: 0.43, 0.76) was greater than that for anal pressure (CCC<\/jats:styled-content> 0.22; 95% CI<\/jats:styled-content>: 0.04, 0.39) and the rectoanal gradient (CCC<\/jats:styled-content> 0.22; 95% CI<\/jats:styled-content>: 0.02, 0.41). Rectal sensory thresholds for first sensation, the desire to defecate, and urgency measured by portable and HRM<\/jats:styled-content> were also significantly correlated between techniques. For several parameters, differences between portable and HRM<\/jats:styled-content> were statistically significant and the Bland Altman test was positive.<\/jats:p><\/jats:sec>Conclusions & Inferences<\/jats:title>Anorectal pressures and rectal sensation can be conveniently measured by portable manometry and are significantly correlated with high\u2010resolution manometry.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12636","type":"journal-article","created":{"date-parts":[[2015,7,31]],"date-time":"2015-07-31T03:09:34Z","timestamp":1438312174000},"page":"1504-1508","source":"Crossref","is-referenced-by-count":16,"title":["A novel technique for bedside anorectal manometry in humans"],"prefix":"10.1111","volume":"27","author":[{"given":"A. E.","family":"Bharucha","sequence":"first","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Stroetz","sequence":"additional","affiliation":[{"name":"Thoracic Diseases Research Unit Division of Pulmonary and Critical Care Medicine Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Feuerhak","sequence":"additional","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. A.","family":"Szarka","sequence":"additional","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. R.","family":"Zinsmeister","sequence":"additional","affiliation":[{"name":"Division of Biostatistics Department of Health Sciences Research Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.10.062"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.190"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.221"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12208"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.061"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02028.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.01.003"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2003.00099.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91748-9"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7337.606"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.28.3.353"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800811143"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-006-0657-4"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01700.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00557.2010"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00099.2012"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12307"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00176.2006"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0774-x"}],"container-title":["Neurogastroenterology & Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnmo.12636","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.12636","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T19:28:39Z","timestamp":1696188519000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.12636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,30]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/nmo.12636"],"URL":"https:\/\/doi.org\/10.1111\/nmo.12636","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"value":"1350-1925","type":"print"},{"value":"1365-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,30]]}}}