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The prevalence has been reported to range from 5% to 40%, largely due to variation from definition criteria and geographical location. Recent published reports in Western and Eastern populations separately indicate that differences in the epidemiology and clinical patterns of <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> may exist. Such differences will have implications for the clinical management of and healthcare strategizing for <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> at the local level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This review aims to examine the prevalence and clinical patterns of <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> in specific groups, namely Western and Eastern populations, based on the Rome criteria. Further differences in the epidemiological associations of <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content> will be explored between population\u2010based studies in both the East and the West. Finally, the socio\u2010economic consequences of <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content>, an important measure of the impact of the disease, will be compared between the East and the West.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12657","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T14:55:59Z","timestamp":1441205759000},"page":"167-174","source":"Crossref","is-referenced-by-count":122,"title":["Clinical and epidemiological differences in functional dyspepsia between the East and the West"],"prefix":"10.1111","volume":"28","author":[{"given":"S.","family":"Mahadeva","sequence":"first","affiliation":[{"name":"Division of Gastroenterology Department of Medicine Faculty of Medicine University Malaya Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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