{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:31:26Z","timestamp":1760189486734},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T00:00:00Z","timestamp":1460073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"USPHS NIH","award":["R01 DK078924"],"award-info":[{"award-number":["R01 DK078924"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pressure drift (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>), resulting from differences between room and body temperature, reduces the accuracy of pressure measurements with the Manoscan high resolution manometry (<jats:styled-content style=\"fixed-case\">HRM<\/jats:styled-content>) system. Our aims were to assess <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> during anorectal <jats:styled-content style=\"fixed-case\">HRM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Defined as the residual pressure measured immediately after the catheter was removed, <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> was calculated for each sensor and averaged across all 12 sensors in 454 anorectal consecutive studies recorded with 3 <jats:styled-content style=\"fixed-case\">HRM<\/jats:styled-content> catheters. The relationship between <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> and study duration, number of prior uses of a catheter, and peak and average pressure exposure during a study were evaluated. The correction of <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> with a software algorithm (thermal compensation) was evaluated in 76 studies where the most distal sensor was outside the body.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> varied among sensors and across catheters. The average <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> (7.3 \u00b1 0.2 mmHg) was significantly greater for newer catheters, during longer studies, or when sensors were exposed to higher pressures. Together, these factors explained 81% of the variance in overall <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>. After thermal compensation, the <jats:italic>uncorrected<\/jats:italic> median <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> for the most distal sensor was 2.5\u20135 mmHg over the study duration. Correcting this changed the interpretation (e.g., as abnormal instead of normal) of at least 1 anorectal parameter in eight of 76 studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>During anorectal <jats:styled-content style=\"fixed-case\">HRM<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> PD<\/jats:styled-content> declines with catheter use and is greater for newer catheters, when sensors are exposed to higher pressures, and for studies of longer duration. While <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> is partially corrected with thermal compensation algorithms, the impact on interpretation is modest.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12830","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T18:35:40Z","timestamp":1460313340000},"page":"1433-1437","source":"Crossref","is-referenced-by-count":8,"title":["Determinants and clinical impact of pressure drift in manoscan anorectal high resolution manometry system"],"prefix":"10.1111","volume":"28","author":[{"given":"G.","family":"Parthasarathy","sequence":"first","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Department of Medicine Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"McMaster","sequence":"additional","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Department of Medicine Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Feuerhak","sequence":"additional","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Department of Medicine Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. R.","family":"Zinsmeister","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics Department of Health Sciences Research Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"Bharucha","sequence":"additional","affiliation":[{"name":"Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program Division of Gastroenterology and Hepatology Department of Medicine Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.10.062"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.190"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm15168"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01817.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12493"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.221"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.10.049"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12636"}],"container-title":["Neurogastroenterology &amp; Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnmo.12830","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.12830","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T14:05:24Z","timestamp":1696169124000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.12830"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,8]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/nmo.12830"],"URL":"https:\/\/doi.org\/10.1111\/nmo.12830","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"value":"1350-1925","type":"print"},{"value":"1365-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,8]]}}}