{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:56:20Z","timestamp":1790517380455,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T00:00:00Z","timestamp":1463529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Municipality of Bergen"},{"DOI":"10.13039\/100010745","name":"Norwegian Medical Association","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100010745","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Irritable bowel syndrome (<jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content>) is a common complication following gastroenteritis, and a high prevalence of postgiardiasis <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> has previously been reported. This study aims to investigate the prevalence, adjusted relative risk (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>adj), and overlap of different functional gastrointestinal disorders (<jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content>) according to Rome <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> criteria following infection with <jats:italic>Giardia lamblia<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients \u226518 years of age with verified giardiasis during an outbreak in 2004, and a control group matched by age and gender, were mailed a questionnaire 3 years later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The prevalence of functional dyspepsia (<jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content>) was 25.9% in the exposed and 6.9% in the control group, <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>adj: 3.9 (95% confidence intervals [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]: 3.1\u20134.8). The prevalence of <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> was 47.9% and 14.3%, respectively, with <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>adj: 3.4 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 3.0\u20133.8). Prevalence of other gastrointestinal symptoms ranged from 70.0% <jats:italic>vs<\/jats:italic> 39.7% for bloating (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>adj: 1.8) to 8.3% <jats:italic>vs<\/jats:italic> 2.9% for nausea (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>adj: 3.0) in the G<jats:italic>iardia<\/jats:italic> and the control group, respectively. Among individuals fulfilling criteria for <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> 44% in the exposed group and 29% in the control group also fulfilled criteria for <jats:styled-content style=\"fixed-case\">FD<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> subtypes based on Rome <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> criteria (stool consistency) showed poor agreement with subtypes based on frequency of bowel movements (Kappa\u2010values: 0.17 and 0.27).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>There were high prevalences and <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>s of <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> FD<\/jats:styled-content> and other gastrointestinal symptoms following acute giardiasis, and a high degree of overlap between the disorders. The agreement between different <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> subtype criteria varied, and there were also differences between the exposed and control group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12856","type":"journal-article","created":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T11:37:48Z","timestamp":1463571468000},"page":"1561-1569","source":"Crossref","is-referenced-by-count":22,"title":["Postinfectious and sporadic functional gastrointestinal disorders have different prevalences and rates of overlap: results from a controlled cohort study 3 years after acute giardiasis"],"prefix":"10.1111","volume":"28","author":[{"given":"K. 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