{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T15:09:38Z","timestamp":1780758578251,"version":"3.54.1"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T00:00:00Z","timestamp":1468454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81200274"],"award-info":[{"award-number":["81200274"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2017,1]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Functional bowel disorders (FBD<\/jats:styled-content>s) such as irritable bowel syndrome (IBS<\/jats:styled-content>) impact on quality of life and health care resources. It is uncertain whether patients with functional digestive symptoms have similar characteristics in different populations. This population\u2010based study assessed the prevalence and identified risk factors for these disorders in South\u2010East China.<\/jats:p><\/jats:sec>Methods<\/jats:title>Five communities were selected at random and invitations distributed to a representative sample (block randomization). Questionnaires were completely supervised by investigators. Demographic and medical data with FBD<\/jats:styled-content> symptoms (Rome III criteria), psychological condition, life event stress, and quality of life were collected.<\/jats:p><\/jats:sec>Key Results<\/jats:title>Functional bowel disorder prevalence was 41.6% in 1999\/2115 (94.5%) completed questionnaires: 9.9% functional constipation (FC<\/jats:styled-content>), 6.8% bloating (FB<\/jats:styled-content>), 6.5% diarrhea (FD<\/jats:styled-content>), 5.9% IBS<\/jats:styled-content> (IBS<\/jats:styled-content>\u2010D 47.1%, IBS<\/jats:styled-content>\u2010M 23.9%, IBS<\/jats:styled-content>\u2010C 12.8%, IBS<\/jats:styled-content>\u2010U 16.2%), and 12.6% unspecified. Similar numbers of men and women had FBD<\/jats:styled-content>s or IBS<\/jats:styled-content> (overall; 51.3% male vs 48.7% female, P<\/jats:italic>=.796); however, there was female predominance in FC<\/jats:styled-content> (62.1%, P<\/jats:italic><.001) and FB<\/jats:styled-content> (58.5%, P<\/jats:italic>=.038). FBD<\/jats:styled-content>s were associated with greater anxiety, depression, life event stress, and a lower quality of life compared with those without symptoms (all, P<\/jats:italic><.0001). Logistic regression identified medical co\u2010morbidity, anxiety\/depression, and life event stress as independent risk factors for these disorders.<\/jats:p><\/jats:sec>Conclusions & Inferences<\/jats:title>Functional bowel disorders are as common in South China as in western populations. A similar number of men and women report FBD<\/jats:styled-content>s and IBS<\/jats:styled-content>. Only FC<\/jats:styled-content> and FB<\/jats:styled-content> are more prevalent in females. Independent risk factors associated with FBD<\/jats:styled-content>s included physical and psychosocial stressors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.12897","type":"journal-article","created":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T10:38:50Z","timestamp":1468492730000},"source":"Crossref","is-referenced-by-count":49,"title":["Prevalence and risk factors for functional bowel disorders in South China: a population based study using the Rome III criteria"],"prefix":"10.1111","volume":"29","author":[{"given":"Y.","family":"Long","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou Zhejiang Province 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Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou Zhejiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Fried","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Hepatology University Hospital Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Fox","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Hepatology University Hospital Z\u00fcrich Z\u00fcrich Switzerland"},{"name":"Abdominal Center: Gastroenterology St. Claraspital Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology 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