{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:35:57Z","timestamp":1790678157167,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T00:00:00Z","timestamp":1477526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002865","name":"Chongqing Science and Technology Commission","doi-asserted-by":"publisher","award":["cstc2013kjrc\u2010ljrccj10003"],"award-info":[{"award-number":["cstc2013kjrc\u2010ljrccj10003"]}],"id":[{"id":"10.13039\/501100002865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The composition of ingested food is important for the gut microbiome and intestinal homeostasis. We have previously demonstrated that the structure and mechanical properties in the small intestine remodel significantly during fasting. However, it is not clear to what extent the intestinal mechanical properties changes when the composition of food is changed. This study aimed to investigate the passive biomechanical properties and intestinal tissue remodeling in rabbits fed a low\u2010residue diet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>New Zealand rabbits (control group n=6, intervention group n=7) were studied. Segments from duodenum, jejunum and ileum were excised. The intestinal diameter and length were obtained from digitized images of the segments at preselected luminal pressure levels and at no\u2010load and zero\u2010stress states. Circumferential and longitudinal stresses (force per area) and strains (deformation) were computed from the length, diameter and pressure data referenced to the zero\u2010stress state geometry. Histomorphometric data were also obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      The wet weight\u2010per\u2010unit length, wall thickness and wall area decreased in the intervention group (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.05,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.01). Histological measurement confirmed that the wall thickness decreased in all three segments, which was primarily due to mucosal thinning (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.05). The opening angle tended to increase in all segments in the intervention group. Significant difference between the two groups was found for the jejunum (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.05). Feeding the low\u2010residue diet shifted the circumferential stress\u2010strain curves in the intervention group to the right, indicating intestinal wall softening.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions &amp; Inferences<\/jats:title>\n                    <jats:p>Low\u2010residue diet in rabbits for 1\u00a0month induces location\u2010dependent histomorphometric and biomechanical remodeling of the intestine.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.12983","type":"journal-article","created":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T22:33:00Z","timestamp":1477607580000},"source":"Crossref","is-referenced-by-count":8,"title":["Low\u2010residue diet fed to rabbits induces histomorphological and biomechanical remodeling of small intestine"],"prefix":"10.1111","volume":"29","author":[{"given":"Y.","family":"Liu","sequence":"first","affiliation":[{"name":"GIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education Bioengineering College Chongqing University  Chongqing China"},{"name":"GIOME Academia Department of Clinical Medicine Aarhus University  Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Zhao","sequence":"additional","affiliation":[{"name":"GIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education Bioengineering College Chongqing University  Chongqing China"},{"name":"GIOME Academia Department of Clinical Medicine Aarhus University  Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Liao","sequence":"additional","affiliation":[{"name":"GIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education Bioengineering College Chongqing University  Chongqing China"},{"name":"GIOME Academia Department of Clinical Medicine Aarhus University  Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Bao","sequence":"additional","affiliation":[{"name":"GIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education Bioengineering College Chongqing University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5792-2845","authenticated-orcid":false,"given":"H.","family":"Gregersen","sequence":"additional","affiliation":[{"name":"GIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education Bioengineering College Chongqing University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2013.07.019"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.01.018"},{"key":"e_1_2_9_4_1","volume-title":"Biomechanics of the Gastrointestinal Tract","author":"Gregersen H","year":"2002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2006.05.008"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015019030514"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-4533(01)00091-1"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2008.11.033"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2016.02.004"},{"issue":"2","key":"e_1_2_9_10_1","first-page":"116","article-title":"Diverticular disease. 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