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A majority of patients also experiences gastrointestinal (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>) symptoms. Furthermore, <jats:styled-content style=\"fixed-case\">JHS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EDS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content> has specifically been shown to be highly prevalent in patients with functional <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> disorders, such as functional dyspepsia and irritable bowel syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this review was to examine the nature of <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> symptoms and their underlying pathophysiology in <jats:styled-content style=\"fixed-case\">JHS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EDS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content>. In addition, we consider the clinical implications of the diagnosis and treatment of <jats:styled-content style=\"fixed-case\">JHS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EDS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HT<\/jats:styled-content> for practicing clinicians in gastroenterology. Observations summarized in this review may furthermore represent the first step toward the identification of a new pathophysiological basis for a substantial subgroup of patients with functional <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> disorders.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13013","type":"journal-article","created":{"date-parts":[[2017,1,14]],"date-time":"2017-01-14T01:08:09Z","timestamp":1484356089000},"source":"Crossref","is-referenced-by-count":76,"title":["Gastrointestinal disorders in joint hypermobility syndrome\/Ehlers\u2010Danlos syndrome hypermobility type: A review for the gastroenterologist"],"prefix":"10.1111","volume":"29","author":[{"given":"A. 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