{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:02:17Z","timestamp":1782777737785,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>After achalasia treatment, a subset of patients has poor esophageal emptying without having symptoms. There is no consensus on whether to pre\u2010emptively treat these patients. We hypothesized that, if left untreated, these patients will experience earlier symptom recurrence than patients without stasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>99 treated achalasia patients who were in clinical remission (Eckardt \u22643) at 3\u00a0months after treatment were divided into two groups, based on presence or absence of esophageal stasis on a timed barium esophagogram performed after 3\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Two years after initial treatment, patients with stasis after treatment still had a wider esophagus (3\u00a0cm; <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>: 2.2\u20103.8) and more stasis (3.5\u00a0cm; <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>: 1.9\u20105.6) than patients without stasis (1.8\u00a0cm wide and 0\u00a0cm stasis; both <jats:italic>P<\/jats:italic>&lt;.001). In patients with stasis, the esophageal diameter had increased from 2.5 to 3.0\u00a0cm within 2\u00a0years of follow\u2010up. The symptoms, need for and time to retreatment were comparable between the two groups. Quality of life and reflux symptoms were also comparable between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>Although patients with stasis initially had a wider esophagus and 2\u00a0years after treatment also had a higher degree of stasis and a more dilated esophagus, compared to patients without stasis, they did not have a higher chance of requiring retreatment. We conclude that stasis in symptom\u2010free achalasia patients after treatment does not predict treatment failure within 2\u00a0years and can therefore not serve as a sole reason for retreatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13059","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T07:53:00Z","timestamp":1489996380000},"source":"Crossref","is-referenced-by-count":15,"title":["Esophageal stasis in achalasia patients without symptoms after treatment does not predict symptom recurrence"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6377-3869","authenticated-orcid":false,"given":"F. B.","family":"van Hoeij","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Academic Medical Center  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. J. P. M.","family":"Smout","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Academic Medical Center  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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