{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:26:28Z","timestamp":1792589188682,"version":"4.5.0"},"reference-count":41,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T00:00:00Z","timestamp":1498089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100001502","name":"Blue Cross Blue Shield of Michigan Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001502","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006324","name":"American Psychological Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006324","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006710","name":"Wayne State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR057808"],"award-info":[{"award-number":["AR057808"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR057047; NIH T32 035165"],"award-info":[{"award-number":["AR057047; NIH T32 035165"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Current clinical guidelines identify several psychological treatments for irritable bowel syndrome (<jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> patients, however, have elevated trauma, life stress, relationship conflicts, and emotional avoidance, which few therapies directly target. We tested the effects of emotional awareness and expression training (<jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content>) compared to an evidence\u2010based comparison condition\u2014relaxation training\u2014and a waitlist control condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adults with <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> (N=106; 80% female, Mean age=36\u00a0years) were randomized to <jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content>, relaxation training, or waitlist control. Both <jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content> and relaxation training were administered in three, weekly, 50\u2010minute, individual sessions. All patients completed the <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> Symptom Severity Scale (primary outcome), <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> Quality of Life, and Brief Symptom Inventory (anxiety, depressive, and hostility symptoms) at pretreatment and at 2\u00a0weeks posttreatment and 10\u00a0weeks follow\u2010up (primary endpoint).<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Compared to waitlist controls, <jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content>, but not relaxation training, significantly reduced <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content> symptom severity at 10\u2010week follow\u2010up. Both <jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content> and relaxation training improved quality of life at follow\u2010up. Finally, <jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content> did not reduce psychological symptoms, whereas relaxation training reduced depressive symptoms at follow\u2010up (and anxiety symptoms at posttreatment).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>Brief emotional awareness and expression training that targeted trauma and emotional conflicts reduced somatic symptoms and improved quality of life in patients with <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content>. This emotion\u2010focused approach may be considered an additional treatment option for <jats:styled-content style=\"fixed-case\">IBS<\/jats:styled-content>, although research should compare <jats:styled-content style=\"fixed-case\">EAET<\/jats:styled-content> to a full cognitive\u2010behavioral protocol and determine which patients are best suited for each approach. Registered at clinicaltrials.gov (NCT01886027).<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13143","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T02:52:50Z","timestamp":1498186370000},"source":"Crossref","is-referenced-by-count":74,"title":["Emotional awareness and expression training improves irritable bowel syndrome: A randomized controlled trial"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2242-2725","authenticated-orcid":false,"given":"E. R.","family":"Thakur","sequence":"first","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"},{"name":"Houston VA HSR&amp;D Center for Innovations in Quality, Effectiveness and Safety Michael E. DeBakey Veterans Affairs Medical Center VA South Central Mental Illness Research, Education and Clinical Center  Houston TX USA"},{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. J.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. A.","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. N.","family":"Carty","sequence":"additional","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. S.","family":"Ziadni","sequence":"additional","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. K.","family":"Doherty","sequence":"additional","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Lackner","sequence":"additional","affiliation":[{"name":"Department of Medicine University at Buffalo School of Medicine SUNY  Buffalo NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Schubiner","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine St. John\/Providence Health System  Southfield MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Lumley","sequence":"additional","affiliation":[{"name":"Department of Psychology Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02463.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000204897.25745.7c"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.09.005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199912000-00009"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07296.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.148"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207284.1998.11491537"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.453"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.12.018"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.4.394"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2005.02.015"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12647"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6811.2009.01216.x"},{"key":"e_1_2_10_15_1","first-page":"190","article-title":"Alexithymia in irritable bowel syndrome","volume":"11","author":"Sayar K","year":"2000","journal-title":"Turk Psikiyatri Derg"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000228247"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X14000041"},{"key":"e_1_2_10_18_1","first-page":"1","article-title":"Psychological treatments for the management of irritable bowel syndrome","volume":"006442","author":"Zijdenbos IL","year":"2009","journal-title":"Cochrane Library"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.061"},{"key":"e_1_2_10_20_1","first-page":"169","volume-title":"Bergin and Garfield's handbook of psychotherapy and behavior change","author":"Lambert MJ","year":"2013"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1997.142318000.x"},{"key":"e_1_2_10_22_1","first-page":"338","article-title":"Study design considerations for irritable bowel syndrome clinical trials","volume":"27","author":"Miller LE","year":"2014","journal-title":"Ann Gastroenterol"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.01941.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018831127942"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700048017"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2015.12.003"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-013-9500-z"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199003000-00002"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.246"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(88)90024-3"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(87)90047-9"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.07.005"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(91)90215-7"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90678-5"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2003.50055"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pra.0000442934.38704.3a"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.139"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-008-9154-7"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-010-9182-8"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-3204.45.2.165"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-007-9127-2"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2001.01010.x"}],"container-title":["Neurogastroenterology &amp; Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnmo.13143","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.13143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T10:13:15Z","timestamp":1696155195000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.13143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,22]]},"references-count":41,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/nmo.13143"],"URL":"https:\/\/doi.org\/10.1111\/nmo.13143","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"value":"1350-1925","type":"print"},{"value":"1365-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,22]]},"article-number":"e13143"}}