{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T14:47:33Z","timestamp":1774622853010,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T00:00:00Z","timestamp":1504569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK073983"],"award-info":[{"award-number":["U01DK073983"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK073975"],"award-info":[{"award-number":["U01DK073975"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK073985"],"award-info":[{"award-number":["U01DK073985"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK074007"],"award-info":[{"award-number":["U01DK074007"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK073974"],"award-info":[{"award-number":["U01DK073974"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK074008"],"award-info":[{"award-number":["U01DK074008"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Wireless motility capsule (\n                      <jats:styled-content style=\"fixed-case\">WMC<\/jats:styled-content>\n                      ) findings are incompletely defined in suspected gastroparesis. We aimed to characterize regional\n                      <jats:styled-content style=\"fixed-case\">WMC<\/jats:styled-content>\n                      transit and contractility in relation to scintigraphy, etiology, and symptoms in patients undergoing gastric emptying testing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 209 patients with gastroparesis symptoms at\n                      <jats:styled-content style=\"fixed-case\">NIDDK<\/jats:styled-content>\n                      Gastroparesis Consortium centers underwent gastric scintigraphy and\n                      <jats:styled-content style=\"fixed-case\">WMC<\/jats:styled-content>\n                      s on separate days to measure regional transit and contractility. Validated questionnaires quantified symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      Solid scintigraphy and liquid scintigraphy were delayed in 68.8% and 34.8% of patients;\n                      <jats:styled-content style=\"fixed-case\">WMC<\/jats:styled-content>\n                      gastric emptying times (\n                      <jats:styled-content style=\"fixed-case\">GET<\/jats:styled-content>\n                      ) were delayed in 40.3% and showed 52.8% agreement with scintigraphy; 15.5% and 33.5% had delayed small bowel (\n                      <jats:styled-content style=\"fixed-case\">SBTT<\/jats:styled-content>\n                      ) and colon transit (\n                      <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content>\n                      ) times. Transit was delayed in \u22652 regions in 23.3%. Rapid transit was rarely observed. Diabetics had slower\n                      <jats:styled-content style=\"fixed-case\">GET<\/jats:styled-content>\n                      but more rapid\n                      <jats:styled-content style=\"fixed-case\">SBTT<\/jats:styled-content>\n                      versus idiopathics (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0\u2264\u00a0.02).\n                      <jats:styled-content style=\"fixed-case\">GET<\/jats:styled-content>\n                      delays related to greater scintigraphic retention, slower\n                      <jats:styled-content style=\"fixed-case\">SBTT<\/jats:styled-content>\n                      , and fewer gastric contractions (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0\u2264\u00a0.04). Overall gastroparesis symptoms and nausea\/vomiting, early satiety\/fullness, bloating\/distention, and upper abdominal pain subscores showed no relation to\n                      <jats:styled-content style=\"fixed-case\">WMC<\/jats:styled-content>\n                      transit. Upper and lower abdominal pain scores (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0\u2264\u00a0.03) were greater with increased colon contractions. Constipation correlated with slower\n                      <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content>\n                      and higher colon contractions (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.03). Diarrhea scores were higher with delayed\n                      <jats:styled-content style=\"fixed-case\">SBTT<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">CTT<\/jats:styled-content>\n                      (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0\u2264\u00a0.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions &amp; Inferences<\/jats:title>\n                    <jats:p>\n                      Wireless motility capsules define gastric emptying delays similar but not identical to scintigraphy that are more severe in diabetics and relate to reduced gastric contractility. Extragastric transit delays occur in &gt;40% with suspected gastroparesis. Gastroparesis symptoms show little association with\n                      <jats:styled-content style=\"fixed-case\">WMC<\/jats:styled-content>\n                      profiles, although lower symptoms relate to small bowel or colon abnormalities.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.13196","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T07:01:01Z","timestamp":1504594861000},"source":"Crossref","is-referenced-by-count":71,"title":["Relating gastric scintigraphy and symptoms to motility capsule transit and pressure findings in suspected gastroparesis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6158-2871","authenticated-orcid":false,"given":"W. L.","family":"Hasler","sequence":"first","affiliation":[{"name":"Division of Gastroenterology University of Michigan  Ann Arbor MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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