{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:51:50Z","timestamp":1777935110218,"version":"3.51.4"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T00:00:00Z","timestamp":1506297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Advances in clinical measurement of esophageal motility and function have improved the assessment of swallowing disorders and reflux symptoms. Variation in data acquisition, analysis, and reporting exists and impacts on diagnosis and management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims and Methods<\/jats:title><jats:p>This study examined variation in esophageal manometry methodology between institutions to establish the status in current practice. A structured survey was distributed through international <jats:styled-content style=\"fixed-case\">NGM<\/jats:styled-content> societies using an Internet\u2010based platform. Questions explored infrastructure, technology, analysis, and reporting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Responses were received from 91 centers from 29 countries. Eighteen (20%) centers used \u201cconventional\u201d manometry, 75 (82%) high\u2010resolution manometry, and 53 (58%) <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> impedance manometry.<\/jats:p><jats:p>All centers documented motility for single water swallows. The Chicago Classification was applied by 65 (71.4%) centers. In contrast, analysis of <jats:styled-content style=\"fixed-case\">EGJ<\/jats:styled-content> morphology varied widely. Adjunctive testing was often applied: multiple rapid swallows (77%), rapid drink challenge (77%), single solid swallows (63%), and a standard test meal (18%).<\/jats:p><jats:p>Of 86 (94.5%) units that offered <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content> impedance (<jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content>\u2010Z) studies, approximately half (53.5%) performed tests on acid\u2010suppressant medication in patients with a high pretest probability (eg, erosive esophagitis). Most (75.6%) centers manually reviewed every reflux event. Others examined <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content>\u2010Z data only prior to symptoms. To assess symptom association with reflux events, 73.6% centers analyzed each symptom separately, whereas 29.7% centers pooled symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Inferences<\/jats:title><jats:p>There is marked variation in the data acquisition, analysis, and reporting of esophageal manometry studies. Further efforts to improve quality and uniformity in testing and reporting are required. This survey provides information upon which best\u2010practice guidelines can be developed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13215","type":"journal-article","created":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T03:27:23Z","timestamp":1506396443000},"source":"Crossref","is-referenced-by-count":38,"title":["Variation in esophageal physiology testing in clinical practice: Results from an international survey"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3742-5163","authenticated-orcid":false,"given":"R.","family":"Sweis","sequence":"first","affiliation":[{"name":"GI Services University College London Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6355-0921","authenticated-orcid":false,"given":"H.","family":"Heinrich","sequence":"additional","affiliation":[{"name":"National Bowel Research Centre &amp; GI Physiology Unit Queen Mary University of London  London 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