{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:41:46Z","timestamp":1756384906775,"version":"3.41.2"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T00:00:00Z","timestamp":1506988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"University of Kelaniya, Sri Lanka"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2018,3]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Aerophagia is a common childhood functional gastrointestinal disorder. We studied the association between adverse life events (ALE<\/jats:styled-content>s), psychological maladjustment, somatization, and aerophagia (AP<\/jats:styled-content>) in adolescents. We also assessed the impact of AP<\/jats:styled-content> on their health\u2010related quality of life (HRQ<\/jats:styled-content>oL).<\/jats:p><\/jats:sec>Methods<\/jats:title>A cross\u2010sectional survey was conducted on 2500 subjects of 13\u201018\u00a0years in 8 randomly selected schools in Sri Lanka. Translated, validated, and self\u2010administered questionnaires were used to collect data. Aerophagia was diagnosed using Rome III<\/jats:styled-content> criteria.<\/jats:p><\/jats:sec>Key Results<\/jats:title>A total of 2453 questionnaires were analyzed (males 1200 [48.9%], mean age 14.8\u00a0years, SD<\/jats:styled-content> 1.6\u00a0years). Of them, 371 adolescents had AP<\/jats:styled-content> (15.1%). Aerophagia was associated with exposure to physical abuse (20.4% vs. 12.7% in controls, P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.0001), emotional abuse (20.3% vs. 8.2% in controls, P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.0001), and other ALE<\/jats:styled-content>s (22% vs. 10.2% in controls, P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.001). One hundred and ninety (51.2%) adolescents with AP<\/jats:styled-content> and 775 (37.2%) controls had a personality score above the international cutoff value of 105, indicating psychological maladjustment (odds ratio 1.77, 95% confidence interval 1.42\u20102.21, P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.0001). Those with AP<\/jats:styled-content> had higher somatization (16.4 vs. 8.9) and lower overall HRQ<\/jats:styled-content>oL scores (77.0 vs. 85.1, P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.0001). HRQ<\/jats:styled-content>oL scores of adolescents with AP<\/jats:styled-content> were lower in all domains, namely, physical (80.6 vs. 86.9), emotional (69.1 vs. 80.3), social (83.8 vs. 90.5), and school (72.6 vs. 82.5) functioning (P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.0001).<\/jats:p><\/jats:sec>Conclusions and Inferences<\/jats:title>Aerophagia was associated with exposure to ALE<\/jats:styled-content>s and psychological maladjustment. Affected teenagers suffer from more somatic symptoms and has a poor HRQ<\/jats:styled-content>oL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13224","type":"journal-article","created":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T08:36:46Z","timestamp":1507019806000},"source":"Crossref","is-referenced-by-count":12,"title":["Aerophagia in adolescents is associated with exposure to adverse life events and psychological maladjustment"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1379-5052","authenticated-orcid":false,"given":"S.","family":"Rajindrajith","sequence":"first","affiliation":[{"name":"Department of Paediatrics Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Hettige","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Gulegoda","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Jayawickrama","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. C.","family":"De Silva","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. K.","family":"Samarakoon","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. L.","family":"de Silva","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Abeyagunawardena","sequence":"additional","affiliation":[{"name":"Teaching Hospital Peradeniya Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. M.","family":"Devanarayana","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine University of Kelaniya Ragama Sri\u00a0Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318236051d"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rgmx.2015.03.008"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001108"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12951"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(86)80108-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2007.01190.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/110241599750006802"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2000.tb00084.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12355"},{"key":"e_1_2_8_11_1","first-page":"961","volume-title":"Rome III: The Functional Gastrointestinal Disorders","author":"Walker LS","year":"2006"},{"key":"e_1_2_8_12_1","first-page":"185","volume-title":"New Psychological Tests and Testing Research","author":"Zoysa P","year":"2007"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022022102033001006"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-200108000-00006"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsn093"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.08.063"},{"key":"e_1_2_8_17_1","first-page":"7","volume-title":"Preventing Child Maltreatment: A Guide to Taking Action and Generating Evidence","author":"Butchart A","year":"2006"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01303162"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000249"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmu035"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-9-6"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/096382899297576"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.4038\/cmj.v53i1.218"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.21779"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-310694"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.05.012"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001006"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-14-150"},{"key":"e_1_2_8_29_1","article-title":"Functional disorder: children and adolescents [published online February 15 2016]","author":"Hyams JS","year":"2016","journal-title":"Gastroenterology"}],"container-title":["Neurogastroenterology & Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnmo.13224","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.13224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T15:59:40Z","timestamp":1694793580000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.13224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,3]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/nmo.13224"],"URL":"https:\/\/doi.org\/10.1111\/nmo.13224","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"type":"print","value":"1350-1925"},{"type":"electronic","value":"1365-2982"}],"subject":[],"published":{"date-parts":[[2017,10,3]]},"article-number":"e13224"}}