{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:16:28Z","timestamp":1762431388090,"version":"3.41.2"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2018,6]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>High\u2010resolution esophageal manometry (HREM<\/jats:styled-content>) has become a leading tool in the assessment of esophageal motor disorders, replacing conventional manometry. However, there is limited data about the contribution of HREM<\/jats:styled-content> as compared with conventional manometry to the assessment of esophageal motor disorders in patients with non\u2010cardiac chest pain (NCCP<\/jats:styled-content>). The aim of the study was to compare the distribution of esophageal motor disorders in patients with NCCP<\/jats:styled-content> using HREM<\/jats:styled-content> as compared with conventional manometry and to determine if HREM<\/jats:styled-content> improved diagnosis of these disorders.<\/jats:p><\/jats:sec>Methods<\/jats:title>In this study, we included 300 consecutive patients with NCCP<\/jats:styled-content> who underwent either HREM<\/jats:styled-content> or conventional manometry over a period of 10\u00a0years. A total of 150 patients had conventional manometry and the other 150 patients HREM<\/jats:styled-content>. The Chicago 3.0 classification and the Castell and Spechler classification were used to determine the esophageal motor disorder of NCCP<\/jats:styled-content> patients undergoing HREM<\/jats:styled-content> and conventional manometry, respectively.<\/jats:p><\/jats:sec>Key Results<\/jats:title>In both HREM<\/jats:styled-content> and the conventional manometry groups, normal esophageal motility was the most frequent finding (47% and 36%; respectively, P<\/jats:italic>\u00a0=\u00a0.054). Hypotensive lower esophageal sphincter was the most common motility disorder identified by conventional manometry (27.3%), while ineffective esophageal motility was the most common esophageal motor disorder identified by HREM<\/jats:styled-content> (25.3%).<\/jats:p><\/jats:sec>Conclusions & Inferences<\/jats:title>There is a discrepancy in the type of esophageal motor disorders identified by HREM<\/jats:styled-content> as compared with conventional manometry in NCCP<\/jats:styled-content> patients. Hypotensive motility disorders are the most commonly diagnosed by both manometric techniques.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13282","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T11:13:15Z","timestamp":1514545995000},"source":"Crossref","is-referenced-by-count":8,"title":["High resolution vs conventional esophageal manometry in the assessment of esophageal motor disorders in patients with non\u2010cardiac chest pain"],"prefix":"10.1111","volume":"30","author":[{"given":"O.","family":"Akinsiku","sequence":"first","affiliation":[{"name":"The Esophageal and Swallowing Center Division of Gastroenterology and Hepatology Case Western Reserve University MetroHealth Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"The Esophageal and Swallowing Center Division of Gastroenterology and Hepatology Case Western Reserve University MetroHealth Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Brunner","sequence":"additional","affiliation":[{"name":"The Esophageal and Swallowing Center Division of Gastroenterology and Hepatology Case Western Reserve University MetroHealth Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ganocy","sequence":"additional","affiliation":[{"name":"The Esophageal and Swallowing Center Division of Gastroenterology and Hepatology Case Western Reserve University MetroHealth Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4807-3052","authenticated-orcid":false,"given":"R.","family":"Fass","sequence":"additional","affiliation":[{"name":"The Esophageal and Swallowing Center Division of Gastroenterology and Hepatology Case Western Reserve University MetroHealth Medical Center 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