{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:04:13Z","timestamp":1793059453766,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T00:00:00Z","timestamp":1516233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2018,6]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n The functional lumen imaging probe (Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n ) is a new technology that measures the distensibility of the anal canal represented by the anal distensibility index. The aims of this study were (i) to compare the anal distensibility index to anal pressure in a cohort of patients with fecal incontinence (\n FI<\/jats:styled-content>\n ) and (ii) to compare the diagnostic value of the Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n to that of high\u2010resolution anorectal manometry (\n HRAM<\/jats:styled-content>\n ) in the same cohort of patients.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Eighty\u2010three consecutive patients with\n FI<\/jats:styled-content>\n who underwent Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n and\n HRAM<\/jats:styled-content>\n assessments were enrolled. The diagnostic value of the Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n was compared to that of\n HRAM<\/jats:styled-content>\n and agreement between Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n and\n HRAM<\/jats:styled-content>\n data was assessed.\n <\/jats:p>\n <\/jats:sec>\n \n Key Results<\/jats:title>\n \n More than 70% of the patients diagnosed with anal deficiency at rest and\/or during voluntary contractions by\n HRAM<\/jats:styled-content>\n had the same diagnosis using the Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n . Two patients with higher distensibility indexes at rest had normal anal resting pressures. Sixteen patients with a normal Endo\n FLIP<\/jats:styled-content>\n \u00ae<\/jats:sup>\n index (ie, normal distensibility index at rest and during voluntary contractions) had an abnormal\n HRAM<\/jats:styled-content>\n result. Seven of these 16 patients (44%) had no sphincter lesion or neuropathic disorder that could explain an abnormal anal sphincter function.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions & Inferences<\/jats:title>\n \n We demonstrated that the anal distensibility index and\n HRAM<\/jats:styled-content>\n results are largely in agreement. We did, however, identify several discrepancies between the two techniques, indicating that they may be complementary.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/nmo.13291","type":"journal-article","created":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T05:36:47Z","timestamp":1516253807000},"source":"Crossref","is-referenced-by-count":25,"title":["The diagnostic value of the functional lumen imaging probe versus high\u2010resolution anorectal manometry in patients with fecal incontinence"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6266-4203","authenticated-orcid":false,"given":"A. M.","family":"Leroi","sequence":"first","affiliation":[{"name":"INSERM U1073 Service de Physiologie Digestive INSERM CIC 1404 Rouen, F\u201076000 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Melchior","sequence":"additional","affiliation":[{"name":"INSERM U1073 Service d'H\u00e9pato\u2010Gastroent\u00e9rologie CHU Rouen Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Charpentier","sequence":"additional","affiliation":[{"name":"Service de Radiologie CHU Rouen Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bridoux","sequence":"additional","affiliation":[{"name":"INSERM U1073 Service de Chirurgie Digestive CHU Rouen Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Savoye\u2010Collet","sequence":"additional","affiliation":[{"name":"Service de Radiologie CHU Rouen Rouen 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0399-8320(06)73076-7"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.07.021"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.047696"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.06.004"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.12.011"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01069.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.01.069"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-012-0871-0"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12028"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12063"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12258"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12740"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0399-8320(04)95012-9"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310005631"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-006-0746-4"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.04.048"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-013-0360-2"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105101"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm16171"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12929"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2807"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.10.022"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.00950.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.221"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2014.12.034"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.40021.x"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1159\/000314588"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-015-1087-7"}],"container-title":["Neurogastroenterology 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