{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:55:40Z","timestamp":1787907340828,"version":"build-2784847793"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T00:00:00Z","timestamp":1534118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001785","name":"Flinders University","doi-asserted-by":"publisher","award":["Seeding Grant"],"award-info":[{"award-number":["Seeding Grant"]}],"id":[{"id":"10.13039\/501100001785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001785","name":"Flinders University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001785","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anodal transcranial direct current stimulation (tDCS) has demonstrated effects on corticobulbar excitability and swallowing function as assessed via clinical rating scales in stroke cohorts. Biomechanical effects of anodal tDCS on swallowing remain largely unexplored. We investigated how anodal tDCS applied over the floor of mouth (FOM) representation on the primary motor cortex affects swallowing biomechanics in healthy participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Anodal and sham tDCS were applied for 20 minutes at 1.5\u00a0mA. Corticobulbar excitability was assessed using motor evoked potentials at baseline and 0, 15, 30 and 45 minutes post\u2010tDCS, as assessed by transcranial magnetic stimulation. Swallowing function was assessed pre\u2010 and post\u2010tDCS using routine clinical assessments (Study 1) and pharyngeal high resolution impedance manometry (Study 2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      Study 1 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a017) showed increased corticobulbar excitability and performance on a skilled swallowing task following anodal wetDCS, but not sham tDCS. In Study 2 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a010) anodal tDCS resulted in increased bolus admittance across the upper esophageal sphincter, but decreased pharyngeal and upper esophageal contractile vigor.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Clinical improvements of dietary intake are likely driven by swallowing neuroplastic reorganization which improves bolus admittance across the upper esophageal sphincter (UES).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Inferences<\/jats:title>\n                    <jats:p>The documented changes make motor cortical application of anodal tDCS a promising adjunct to swallowing rehabilitation practice.<\/jats:p>\n                  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