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This study aimed to assess the prevalence and risk factors for IBS in a general adult population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Study of Health in Pomerania (SHIP) is a population\u2010based cohort study in northeastern Germany. SHIP\u2010Trend\u20100 participants enrolled from 2008 to 2012 were grouped according to Rome III criteria (main criteria: abdominal discomfort or crampy or bloating pain for at least six months plus 2\/3 additional criteria). Factors associated with IBS were assessed using survey\u2010weighted backward stepwise logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The final data set included 4194 records. IBS prevalence was 3.5% (3.0%\u20104.2%). Unemployment (OR: 2.02, 1.26\u20103.21), headaches (OR: 2.37, 1.59\u20103.52), mental quality of life (OR: 0.95 per unit increase, 0.93\u20100.97), and interactions between gender and physical quality of life (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.004) and gender and alexithymia (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.002) predicted IBS probability. The model resulted in a good discrimination (area under the curve\u00a0=\u00a075.4%) and model fit (<jats:italic>F<\/jats:italic>\u00a0=\u00a00.72, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.69). History of depression (OR: 2.77, 1.94\u20103.95), back pain (OR: 2.38, 1.69\u20103.35), early trauma (OR: 1.03, 1.02\u20101.04), and duration of inpatient treatment within the last twelve months (OR: 1.02, 1.01\u20101.04) lost their significance in multivariable analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>IBS prevalence was relatively low compared to other studies. Factors predicting IBS were of biological, psychological, and social nature. The association between IBS and pain in different areas of the body indicates a potential underlying complex somatic symptom disorder.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13511","type":"journal-article","created":{"date-parts":[[2018,11,16]],"date-time":"2018-11-16T06:41:45Z","timestamp":1542350505000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Irritable bowel syndrome, mental health, and quality of life: Data from a population\u2010based survey in Germany (SHIP\u2010Trend\u20100)"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9847-130X","authenticated-orcid":false,"given":"Birgit","family":"Schauer","sequence":"first","affiliation":[{"name":"Institute for Community Medicine University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3684-4208","authenticated-orcid":false,"given":"Hans J.","family":"Grabe","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0154-7353","authenticated-orcid":false,"given":"Till","family":"Ittermann","sequence":"additional","affiliation":[{"name":"Institute for Community Medicine University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9643-8263","authenticated-orcid":false,"given":"Markus M.","family":"Lerch","sequence":"additional","affiliation":[{"name":"Department of Medicine A University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3369-6369","authenticated-orcid":false,"given":"Frank U.","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Medicine A University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"M\u00f6nnikes","sequence":"additional","affiliation":[{"name":"Martin Luther\u2010Hospital Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7003-399X","authenticated-orcid":false,"given":"Henry","family":"V\u00f6lzke","sequence":"additional","affiliation":[{"name":"Institute for Community Medicine University Medicine Greifswald Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8873-0486","authenticated-orcid":false,"given":"Paul","family":"Enck","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine VI: Psychosomatic Medicine and Psychotherapy University Hospital Tuebingen Tuebingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5224-4881","authenticated-orcid":false,"given":"Juliane","family":"Schwille\u2010Kiuntke","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine VI: Psychosomatic Medicine and Psychotherapy University Hospital Tuebingen Tuebingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,15]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.7326\/0003-4819-134-9_Part_2-200105011-00010"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1053\/j.gastro.2005.11.061"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1038\/nrdp.2016.14"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1136\/bmj.2.6138.653"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0016-5085(84)90119-7","article-title":"Paulus W. 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