{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:35:30Z","timestamp":1792510530913,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T00:00:00Z","timestamp":1544400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Idiopathic Esophago\u2010gastric outflow obstruction (EGJOO) is a new clinical entity resulting in delayed esophageal emptying secondary to a poorly relaxing lower esophageal sphincter. Little is known about treatment outcomes of idiopathic EGJOO patients.<\/jats:p><jats:p>The aim of this study was to investigate the clinical response of pneumatic dilation (PD) in idiopathic EGJOO patients with a standing barium column and\/or with pill arrest on timed barium esophagram (TBE) before and after undergoing PD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Idiopathic EGJOO patients with retained liquid barium on TBE at 1\u00a0minute and\/or with pill arrest in esophagus at 5\u00a0minutes were included. Patients were treated with PD and evaluated with post\u2010procedural TBE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 33 patients with Idiopathic EGJOO and poor esophageal emptying on TBE were treated with PD. 67% of Idiopathic EGJOO patients reported subjective symptom relief, 18% improved and symptoms later recurred, 6% were lost to follow up, and 9% reported no change. TBE results of pre\u2010PD showed 1\u00a0minute average barium column height of 11.0 cm and 1\u00a0minute barium column width of 1.7 cm. There was significant decrease in 1\u00a0minute liquid barium column height and width (<jats:italic>P<\/jats:italic> &lt; 0.001 and &lt;0.001, respectively) as well as significant improvement in pill passing (<jats:italic>P<\/jats:italic> &lt; 0.006) after undergoing PD. No complications occurred after PD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PD is an effective initial treatment for Idiopathic EGJOO patients with abnormal TBE. Pneumatic dilation relieved symptoms and improved esophageal emptying in Idiopathic EGJOO patients on TBE<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13522","type":"journal-article","created":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T06:36:42Z","timestamp":1544510202000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Pneumatic dilation improves esophageal emptying and symptoms in patients with idiopathic esophago\u2010gastric junction outflow obstruction"],"prefix":"10.1111","volume":"31","author":[{"given":"Steven B.","family":"Clayton","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Wake Forest University Baptist Medical Center  Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire M.","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Medicine University of South Carolina School of Medicine Greenville  Greenville South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Ewing","sequence":"additional","affiliation":[{"name":"Department of Medicine University of South Carolina School of Medicine Greenville  Greenville South Carolina"},{"name":"Greenville Health System Greenville South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Blonski","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Digestive Diseases University of South Florida Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Richter","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Joy McCann Culverhouse Center for Swallowing Disorders University of South Florida Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,10]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01834.x"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.12.041"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.169.2.9242756"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.03.176"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01209.x"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2008.00914.x"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-017-0568-7"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.370"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.435"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60651-0"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31815ea291"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12314"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.giec.2014.07.001"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2005.00661.x"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-2961-6"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.04.048"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-0975-7"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13061"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2010.01604.x"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12625"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12708"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/dox004"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.2.231"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-017-0544-2"}],"container-title":["Neurogastroenterology &amp; 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