{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:17:39Z","timestamp":1784031459761,"version":"3.55.0"},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T00:00:00Z","timestamp":1556236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2019,7]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>The cerebellum has been showed by numerous studies to be active during the process of swallowing. Cortically targeted repetitive transcranial magnetic stimulation (rTMS<\/jats:styled-content>) is a technique which has been shown to result in beneficial electrophysiological and behavioral changes in healthy participants and patients with post stroke dysphagia. Cerebellar rTMS<\/jats:styled-content> is a relatively unstudied area of this emerging field. Here we apply cerebellar targeted rTMS<\/jats:styled-content> to a patient with post stroke dysphagia in an attempt to improve their swallowing.<\/jats:p><\/jats:sec>Methods<\/jats:title>A 67\u2010year\u2010old woman with post stroke dysphagia was recruited to undergo a crossover active rTMS<\/jats:styled-content> vs sham rTMS<\/jats:styled-content> study. Outcome measures were pharyngeal motor evoked potential (PMEP<\/jats:styled-content>) amplitude and cumulative penetration\u2010aspiration score (cPAS<\/jats:styled-content>). The patient attended the laboratory on two occasions. During each attendance, baseline PMEP<\/jats:styled-content> and cPAS<\/jats:styled-content> measurements were acquired followed by either active or sham rTMS<\/jats:styled-content>. Following this, PMEP<\/jats:styled-content> and cPAS<\/jats:styled-content> measurements were repeated at 30\u00a0minutes.<\/jats:p><\/jats:sec>Results<\/jats:title>Active cerebellar rTMS<\/jats:styled-content> was able to increase both PMEP<\/jats:styled-content> amplitude (55% over baseline) and improve swallowing safety (17% below baseline). Sham rTMS<\/jats:styled-content> did not result in any beneficial PMEP<\/jats:styled-content> or cPAS<\/jats:styled-content> changes.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our results suggest that cerebellar rTMS<\/jats:styled-content> has plausible therapeutic potential for post stroke dysphagia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13609","type":"journal-article","created":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T07:12:56Z","timestamp":1556262776000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Rapid improvement in brain and swallowing behavior induced by cerebellar repetitive transcranial magnetic stimulation in poststroke dysphagia: A single patient case\u2010controlled study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2329-0616","authenticated-orcid":false,"given":"Dipesh H.","family":"Vasant","sequence":"first","affiliation":[{"name":"Neurogastroenterology Manchester University Foundation Trust Wythenshawe Hospital Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2050-0726","authenticated-orcid":false,"given":"Ayodele","family":"Sasegbon","sequence":"additional","affiliation":[{"name":"Gastrointestinal (GI) Sciences Division of Diabetes, Endocrinology and Gastroenterology School of Medical Sciences Salford Royal Hospital (part of the Manchester Academic Health Sciences Center (MAHSC)) University of Manchester Salford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia","family":"Michou","sequence":"additional","affiliation":[{"name":"Department of Speech and Language Therapy Technological Educational Institute of Western Greece Patras Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Smith","sequence":"additional","affiliation":[{"name":"Manchester Centre for Clinical Neurosciences Division of Cardiovascular Sciences University of Manchester Salford Royal Hospital Manchester Academic Health Sciences Centre (MAHSC) Salford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaheen","family":"Hamdy","sequence":"additional","affiliation":[{"name":"Gastrointestinal (GI) Sciences Division of Diabetes, Endocrinology and Gastroenterology School of Medical Sciences Salford Royal Hospital (part of the Manchester Academic Health Sciences Center (MAHSC)) University of Manchester Salford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.263475"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.04.056"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2013.09.005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-002-0088-x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199909)46:3<281::AID-ANA2>3.0.CO;2-L"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13100"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01747.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP270817"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP277545"},{"key":"e_1_2_10_11_1","first-page":"A269","article-title":"Ten hz repetitive cerebellar magnetic stimulation reverses cortical suppression in the healthy human pharyngeal motor system","volume":"66","author":"Watanabe M","year":"2017","journal-title":"Gut"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00417897"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(98)70081-2"}],"container-title":["Neurogastroenterology & 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