{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:17:30Z","timestamp":1787015850595,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T00:00:00Z","timestamp":1583798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Parkinson's Disease Foundation, Denmark"},{"name":"The Foundation of July 2, 1984, Denmark"},{"name":"The Lundbeck Foundation"},{"name":"The Novonordisk Foundation"},{"name":"Queen Mary University of London through in-house departmental funds"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Motilis 3D\u2010Transit system allows ambulatory description of transit patterns throughout the gastrointestinal tract and offers an alternative method for studying gastric motility. We aimed to establish normative values for gastric motility assessed with the method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A total of 132 healthy volunteers ingested the 3D\u2010Transit capsule for assessment of gastrointestinal transit times. Recordings from 125 subjects were used for definition of normative values. Forty\u2010six subjects were studied on two consecutive days. Recordings were reanalyzed using newly developed software providing information on gastric emptying (GE) as well as contraction frequency and movement during gastric contractions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median GE time was 2.7\u00a0hours (range 0.1\u201021.2). In 89% of subjects, the capsule passed the pylorus within a postingestion period of 6\u00a0hours. The median frequency of gastric contractions was 3.1 per minute (range 2.6\u20103.8). The frequency was higher in women (3.2, range 2.7\u20103.8) than in men (3.0, range 2.6\u20103.5) and increased with age (0.004 per year) (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). The median amplitudes were 35\u00b0 (range 4\u201085) when based on rotation of the capsule and 11\u00a0mm (range 6\u201031) when based on capsule change in position. The rotation amplitude was higher in women and decreased with increasing BMI (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). The position amplitude was also higher in women and increased with the amount of calories in the test meal, but decreased with increasing BMI and age (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). Day\u2010to\u2010day variation (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&gt;\u00a0.05) was considerable while inter\u2010rater variability was small.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Inferences<\/jats:title>\n                    <jats:p>We have established normative values for gastric motility assessed with the 3D\u2010Transit system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.13829","type":"journal-article","created":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T11:57:58Z","timestamp":1583841478000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Normative values for gastric motility assessed with the 3D\u2010transit electromagnetic tracking system"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0107-4576","authenticated-orcid":false,"given":"Nanna","family":"Sutter","sequence":"first","affiliation":[{"name":"Neurogastroenterology Unit Department of Hepatology and Gastroenterology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4412-4307","authenticated-orcid":false,"given":"Mette Winther","family":"Klinge","sequence":"additional","affiliation":[{"name":"Neurogastroenterology Unit Department of Hepatology and Gastroenterology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-7430","authenticated-orcid":false,"given":"Esben Bolvig","family":"Mark","sequence":"additional","affiliation":[{"name":"Mech\u2010Sense Department of Gastroenterology and Hepatology Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8593-8991","authenticated-orcid":false,"given":"Gursharan","family":"Nandhra","sequence":"additional","affiliation":[{"name":"GI Physiology Unit The Blizard Institute, Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK"},{"name":"Clinical Physics Barts Health NHS Trust The Royal London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Mette","family":"Haase","sequence":"additional","affiliation":[{"name":"Neurogastroenterology Unit Department of Hepatology and Gastroenterology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0251-6049","authenticated-orcid":false,"given":"Jakob","family":"Poulsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline","family":"Knudsen","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and PET Centre Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Borghammer","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and PET Centre Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Schlageter","sequence":"additional","affiliation":[{"name":"Motilis Medica SA Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Birch","sequence":"additional","affiliation":[{"name":"GI Physiology Unit The Blizard Institute, Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK"},{"name":"Clinical Physics Barts Health NHS Trust The Royal London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7997-1533","authenticated-orcid":false,"given":"S. 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