{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T04:59:56Z","timestamp":1774414796296,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>It is unknown whether surgically treated achalasia cases regain or surpass their usual weight into obesity or overweight in the long\u2010term post\u2010operative period. Here, we aimed to assess the incidence of overweight\/obesity (Ob\/Ow) and the risk for reoccurrence up to 48\u00a0months post\u2010laparoscopic Heller myotomy (LHM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a cohort of 114 achalasia cases undergoing LHM. All patients had a confirmed diagnosis of achalasia and had no added comorbidities. We followed up the body mass index (BMI) at the immediate post\u2010operative period, and at one\u2010, six\u2010, 12\u2010, 24\u2010, and 48\u00a0months after LHM. We measured the incidence of Ob\/Ow and its reoccurrence risk with Cox regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results and Conclusions<\/jats:title><jats:p>In the immediate post\u2010operative period, the incidence of Ob\/Ow was significantly less than the usual BMI (before the onset of symptoms) (28.2% vs 66.3%). From the sixth to the 48th month, there was a progressive increase in the incidence of Ob\/Ow and at this timepoint the percent of Ob\/Ow was not statistically different from the usual BMI. The most significant hazard for Ob\/Ow reoccurrence in the long term following LHM is a usual BMI with obesity grade I or III and males lacking pre\u2010surgical weight loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Inferences<\/jats:title><jats:p>Achalasia cases undergoing surgical treatment should be monitored closely in the post\u2010operative period for weight regain, regardless of their pre\u2010operative BMI. Notably, males who before the onset of symptoms were obese or overweight are at significantly increased risk of regaining or surpassing their weight, despite most having lost weight pre\u2010surgically.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13921","type":"journal-article","created":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T02:17:21Z","timestamp":1592446641000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term risk of adult overweight and obesity among achalasia patients who underwent Heller Myotomy"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0731-2464","authenticated-orcid":false,"given":"Andric C.","family":"Perez\u2010Ortiz","sequence":"first","affiliation":[{"name":"Department of Experimental Surgery Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n Mexico City Mexico"},{"name":"Escuela de Medicina Universidad 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