{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:57:54Z","timestamp":1790517474345,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T00:00:00Z","timestamp":1594857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Patients with symptoms of gastroparesis\/dyspepsia often avoid foods or restrict eating for symptom management. There is growing interest in understanding risk for feeding\/eating disorders (FEDs) like avoidant\/restrictive food intake disorder (ARFID). Among patients presenting with gastroparesis\/dyspepsia symptoms, we aimed to determine: (a) FED symptom frequency, and (b) relation of FED symptoms to gastrointestinal symptom severity and gastric retention abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adult patients (N\u00a0=\u00a0288; 78% female) referred for gastroparesis\/dyspepsia symptoms at two academic medical centers from January 2018\u2014February 2019 completed self\u2010report surveys for gastrointestinal symptom severity and FED symptoms. Gastric retention data were available for 210 patients, using 4\u2010hour EggBeater gastric emptying scintigraphy (GES).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Clinically significant FED symptoms were present in 158 patients (54.9%). Interestingly, 115 patients (39.9%) met conservative self\u2010report cutoff for ARFID symptoms, with 67 (23.3%) patients having documented psychosocial\/medical impairment. Of those with survey data for other FEDs (n\u00a0=\u00a0239), only 28 patients (11.7%) had restrictive eating disorders (anorexia nervosa; unspecified FED). Likelihood of having FED symptoms was significantly associated with greater gastroparesis symptom severity (OR\u00a0=\u00a02.23,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001), but not GES. In addition, gastroparesis symptom severity was moderately and significantly associated with greater ARFID symptom severity (\n                      <jats:italic>b<\/jats:italic>\n                      = 0.45,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001), but neither GES nor other FED symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In patients presenting with gastroparesis\/dyspepsia symptoms, FED symptoms were frequent (55%), particularly ARFID, and were associated with greater gastrointestinal symptom severity, but not gastric retention. Gastroparesis\/dyspepsia symptoms may mimic FEDs, particularly ARFID. Clinicians should be cautious about diagnosing ARFID in gastroparesis\/dyspepsia patients, and screening for ARFID could assist behavioral treatment referral.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.13931","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T20:59:03Z","timestamp":1594933143000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["Avoidant\/restrictive food intake disorder symptoms are frequent in patients presenting for symptoms of gastroparesis"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2059-3256","authenticated-orcid":false,"given":"Helen","family":"Burton Murray","sequence":"first","affiliation":[{"name":"Department of Psychiatry Eating Disorders Clinical and Research Program Massachusetts General Hospital Boston Massachusetts USA"},{"name":"Harvard Medical School Boston Massachusetts USA"},{"name":"Neuroenteric Research Laboratory Massachusetts General Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3178-6264","authenticated-orcid":false,"given":"Asad","family":"Jehangir","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Temple University Hospital Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2732-6724","authenticated-orcid":false,"given":"Casey J.","family":"Silvernale","sequence":"additional","affiliation":[{"name":"Neuroenteric Research Laboratory Massachusetts General Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braden","family":"Kuo","sequence":"additional","affiliation":[{"name":"Harvard Medical School Boston Massachusetts USA"},{"name":"Neuroenteric Research Laboratory Massachusetts General Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry P.","family":"Parkman","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Temple University Hospital Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.09.055"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-318712"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-306084"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm18162"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000445226"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01434.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-015-3651-7"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4456-7"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.10.015"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.05.030"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.373"},{"key":"e_1_2_8_13_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders (DSM\u20105)","author":"APA","year":"2013"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-017-0795-5"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.24890\/pc"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23042"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000099"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.08.018"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22462"},{"key":"e_1_2_8_20_1","volume-title":"Cognitive\u2010behavioral therapy for avoidant\/restrictive food intake disorder: children, adolescents, and adults","author":"Thomas JJ","year":"2019"},{"key":"e_1_2_8_21_1","volume-title":"Cognitive behavior therapy and eating disorders","author":"Fairburn CG","year":"2008"},{"key":"e_1_2_8_22_1","volume-title":"intensive CBT for Normal Weight Eating\u2010Disordered Outpatients: What Can One Achieve in Just Ten Sessions?","author":"Brief WG","year":"2016"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20936"},{"key":"e_1_2_8_24_1","unstructured":"MurrayHB BaileyAP KeshishianA et al.Is it ARIFD a Gastrointestinal Disorder or Both? 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