{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T13:15:21Z","timestamp":1754486121252,"version":"3.41.2"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Dyspeptic symptoms are not well correlated with gastric emptying (GE) results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine (a) prevalence of delayed SB transit (SBT) in patients undergoing GE scintigraphy for symptoms of gastroparesis; (b) symptoms associated with delayed SBT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with symptoms of gastroparesis underwent combined GE and SBT scintigraphy (GES\/SBTS). Patients ingested a mixed solid (S)\u2010liquid (L) meal with egg whites labeled with 500\u00a0\u00b5Ci Tc\u201099\u00a0m sulfur colloid and water with 125\u00a0\u00b5Ci In\u2010111 DTPA. Retained S and L gastric activity and percent of L In\u2010111 activity in terminal ileum (TI) and\/or cecum\/colon at 6\u00a0h were determined. Patient Assessment of Gastrointestinal Symptoms (PAGI\u2010SYM) assessed symptoms from 0 (none) to 5 (very severe).<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Of 363 patients, 174 (47.9%) had delayed S GE, 141 (38.8%) delayed L GE, and 70 (19.3%) delayed SBT. Delayed SBT was seen in 24 (6.6%) with normal S GE and 46 (12.7%) with delayed S GE. Patients with isolated delayed SBT had highest symptom scores for postprandial fullness (3.5), stomach fullness (3.4), nausea (3.2), bloating (3.2), compared to isolated delayed S GE who had highest symptom scores for postprandial fullness (3.7), nausea (3.6), stomach fullness (3.4), and early satiety (3.3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>Delayed SBT occurred in 19.3% of dyspeptic patients using GES\/SBTS. While postprandial and stomach fullness were common to both delayed S GE and delayed SBT, early satiety was associated with delayed S GE whereas bloating was associated with delayed SBT. Thus, SBTS can augment GES to help explain some symptoms associated with dyspepsia and suspected gastroparesis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.13987","type":"journal-article","created":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T02:31:02Z","timestamp":1601433062000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Addition of small\u2010bowel transit scintigraphy to gastric emptying for assessment of patients with upper gastrointestinal symptoms"],"prefix":"10.1111","volume":"33","author":[{"given":"Alan H.","family":"Maurer","sequence":"first","affiliation":[{"name":"Division of Nuclear Medicine and Molecular Imaging Department of Radiology Temple University School of Medicine  Philadelphia Pennsylvania USA"},{"name":"Section of Gastroenterology Department of Medicine Temple University School of Medicine  Philadelphia Pennsylvania 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