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As symptoms do not distinguish between patients with and without functional defecation disorder, Rome IV criteria recommend that this disorder is diagnosed when two of three tests are positive: balloon expulsion test (BET), anorectal manometry (ARM), and defecography. However, previous studies have demonstrated that the agreement among these tests is limited. In this issue of Neurogastroenterology and Motility, Sharma et al tested the hypothesis that conducting the ARM in a seated position would increase the diagnostic accuracy of the test in discriminating between patients with normal and prolonged BET. This minireview discusses the current knowledge on the role of the techniques to diagnose defecation disorder and the potential role of the ARM in a seated position.<\/jats:p>","DOI":"10.1111\/nmo.14001","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T11:42:09Z","timestamp":1601379729000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Seated anorectal manometry during simulated evacuation: A physiologic exercise or a new clinically useful diagnostic test?"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5043-9666","authenticated-orcid":false,"given":"Guido","family":"Basilisco","sequence":"first","affiliation":[{"name":"Gastroenterology and Endoscopy Unit Fondazione IRCCS C\u00e0 Granda Ospedale Maggiore Policlinico  Milano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2957-4684","authenticated-orcid":false,"given":"Maura","family":"Corsetti","sequence":"additional","affiliation":[{"name":"NIHR Nottingham Biomedical Research Centre (BRC) Nottingham University Hospitals NHS Trust and the University of Nottingham  Nottingham UK"},{"name":"Nottingham Digestive Diseases Centre School of Medicine University of Nottingham  Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1038\/ajg.2011.164"},{"key":"e_1_2_7_3_1","first-page":"261","article-title":"The economic burden of constipation therapy","volume":"92","author":"Albu A","year":"2019","journal-title":"Med Pharm Rep"},{"doi-asserted-by":"publisher","key":"e_1_2_7_4_1","DOI":"10.1177\/2050640614528175"},{"doi-asserted-by":"publisher","key":"e_1_2_7_5_1","DOI":"10.1038\/ajg.2010.200"},{"doi-asserted-by":"publisher","key":"e_1_2_7_6_1","DOI":"10.1053\/j.gastro.2016.02.009"},{"doi-asserted-by":"publisher","key":"e_1_2_7_7_1","DOI":"10.1111\/j.1572-0241.1998.01019.x"},{"doi-asserted-by":"publisher","key":"e_1_2_7_8_1","DOI":"10.1016\/j.dld.2013.03.016"},{"doi-asserted-by":"publisher","key":"e_1_2_7_9_1","DOI":"10.1007\/BF02066978"},{"doi-asserted-by":"publisher","key":"e_1_2_7_10_1","DOI":"10.1111\/apt.15289"},{"doi-asserted-by":"publisher","key":"e_1_2_7_11_1","DOI":"10.1111\/apt.15657"},{"doi-asserted-by":"publisher","key":"e_1_2_7_12_1","DOI":"10.1038\/nrgastro.2018.27"},{"doi-asserted-by":"publisher","key":"e_1_2_7_13_1","DOI":"10.1016\/j.cgh.2014.03.013"},{"doi-asserted-by":"publisher","key":"e_1_2_7_14_1","DOI":"10.1111\/j.1365-2036.2011.04653.x"},{"doi-asserted-by":"publisher","key":"e_1_2_7_15_1","DOI":"10.1111\/nmo.13125"},{"doi-asserted-by":"publisher","key":"e_1_2_7_16_1","DOI":"10.1007\/BF02052140"},{"doi-asserted-by":"publisher","key":"e_1_2_7_17_1","DOI":"10.1111\/j.1572-0241.2006.00827.x"},{"doi-asserted-by":"publisher","key":"e_1_2_7_18_1","DOI":"10.1111\/nmo.12997"},{"doi-asserted-by":"publisher","key":"e_1_2_7_19_1","DOI":"10.1111\/nmo.13679"},{"doi-asserted-by":"publisher","key":"e_1_2_7_20_1","DOI":"10.1111\/apt.15039"},{"doi-asserted-by":"publisher","key":"e_1_2_7_21_1","DOI":"10.1111\/nmo.13314"},{"doi-asserted-by":"publisher","key":"e_1_2_7_22_1","DOI":"10.1111\/nmo.13608"},{"doi-asserted-by":"publisher","key":"e_1_2_7_23_1","DOI":"10.1111\/nmo.13910"},{"key":"e_1_2_7_24_1","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1136\/bmj.330.7493.724","article-title":"Evidence based diagnostics","volume":"26","author":"Gluud C","year":"2005","journal-title":"BMJ"},{"doi-asserted-by":"publisher","key":"e_1_2_7_25_1","DOI":"10.1111\/nmo.12477"},{"doi-asserted-by":"publisher","key":"e_1_2_7_26_1","DOI":"10.1136\/gutjnl-2014-308835"},{"doi-asserted-by":"publisher","key":"e_1_2_7_27_1","DOI":"10.1259\/bjr\/28989463"},{"doi-asserted-by":"publisher","key":"e_1_2_7_28_1","DOI":"10.1111\/j.1365-2168.1997.00611.x"},{"doi-asserted-by":"publisher","key":"e_1_2_7_29_1","DOI":"10.1111\/codi.13775"},{"doi-asserted-by":"publisher","key":"e_1_2_7_30_1","DOI":"10.1111\/nmo.13762"},{"doi-asserted-by":"publisher","key":"e_1_2_7_31_1","DOI":"10.1016\/j.jpsychores.2017.06.005"}],"container-title":["Neurogastroenterology &amp; 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