{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T03:42:51Z","timestamp":1781322171755,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T00:00:00Z","timestamp":1607644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>High\u2010resolution manometry (HRM) is a key method to evaluate esophageal motility disorders. Current evaluation is usually performed with single water swallows (SWS) that may not challenge esophageal function or reproduce symptoms. Solid food swallows (SFS) could increase the diagnostic yield for clinically relevant disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with dysphagia referred for esophageal HRM during a 2\u2010year period in a single center were reviewed retrospectively and included if SFS was performed during HRM. Chicago classification v3.0 was used to define esophageal motility disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>One hundred and four patients with dysphagia were included (59% women, mean age 57\u00a0years). Ineffective esophageal motility was the most frequent motility disorder. Compared to SWS, the diagnosis changed after SFS in 33 patients (31.7%) including a change from normal or minor diagnosis toward major motility disorders in 14 (13.4%). Fifteen subjects (14.4%) shifted from a minor disorder on SWS to normal after SFS. SFS changed the diagnosis in 53.8% of patients with previous surgery versus 29.5% of those without (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.023). Pressurization during rapid drink challenge was more frequent when SFS changed the diagnosis to major motility disorders (69.2% vs. 37.3%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.033). Twenty\u2010nine percent of patients reported symptoms during SFS, mostly those with diagnostic change to major disorders after SFS (71.4% of patients with changes to major disorders vs. 22.2% of patients without, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion &amp; Inferences<\/jats:title><jats:p>Solid food swallows is a simple way to improve the diagnostic yield of HRM in patients with dysphagia and should be added to manometry protocol in daily clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14060","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T04:03:20Z","timestamp":1607745800000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Diagnostic yield of adding solid food swallows during high\u2010resolution manometry in esophageal motility disorders"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7827-8019","authenticated-orcid":false,"given":"Isis K.","family":"Araujo","sequence":"first","affiliation":[{"name":"Endoscopy and Motility Unit Gastroenterology Department Hospital Cl\u00ednic de Barcelona Barcelona Spain"},{"name":"Digestive Physiology Hopital E Herriot Hospices Civils de Lyon Universit\u00e9 de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7798-7638","authenticated-orcid":false,"given":"Sabine","family":"Roman","sequence":"additional","affiliation":[{"name":"Digestive Physiology Hopital E Herriot Hospices Civils de Lyon Universit\u00e9 de Lyon Lyon France"},{"name":"Digestive Physiology Lyon I University Universit\u00e9 de Lyon Lyon France"},{"name":"LabTAU Inserm U1032 Universit\u00e9 de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Napol\u00e9on","sequence":"additional","affiliation":[{"name":"Digestive Physiology Hopital E Herriot Hospices Civils de Lyon Universit\u00e9 de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2908-1591","authenticated-orcid":false,"given":"Fran\u00e7ois","family":"Mion","sequence":"additional","affiliation":[{"name":"Digestive Physiology Hopital E Herriot Hospices Civils de Lyon Universit\u00e9 de Lyon Lyon France"},{"name":"Digestive Physiology Lyon I University Universit\u00e9 de Lyon Lyon France"},{"name":"LabTAU Inserm U1032 Universit\u00e9 de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.18900.1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12314"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12477"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.13"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12914"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm18054"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13480"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13574"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12252"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(17)30151-6"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(17)30148-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13287"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2009.04142.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12889"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14605"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13021"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520701679603"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.04.181"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13584"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01273.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.289"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12902"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm18038"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13293"},{"key":"e_1_2_8_26_1","first-page":"e14008","article-title":"The added value of symptom analysis during a rapid drink challenge in high\u2010resolution esophageal manometry","author":"Zerbib F","year":"2020","journal-title":"Neurogastroenterol Motil"}],"container-title":["Neurogastroenterology &amp; 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