{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:08:26Z","timestamp":1776269306025,"version":"3.50.1"},"reference-count":53,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>Gastric emptying (GE) requires precise antropyloroduodenal coordination for effective transpyloric flow, the mechanisms of which are still unclear. We aimed to correlate gastric antral function assessed by antroduodenal manometry (ADM) with GE scintigraphy (GES) for liquid feeds in children with suspected gastrointestinal dysmotility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Children who underwent both ADM and GES over a five\u2010year period were reviewed. ADM tracings were re\u2010analyzed to assess antral frequency, amplitude, and motility index (MI) pre\u2010prandially and postprandially. Transpyloric propagation (TPP) was defined as antegrade propagated antral activity preceding duodenal phase III of the migrating motor complex (MMC). TPP was defined as \u201cpoor\u201d if occurring in &lt;50% of all presented duodenal phases III. For GES, regions of interest over the whole stomach, fundus, and antrum were drawn to calculate GE half\u2010time (GE\u2010T<jats:sub>1\/2<\/jats:sub>) and retention rate (RR) in each region at 1 and 2\u00a0h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010seven children (median age: 7.0\u00a0years) were included. Twenty\u2010two had PIPO, 14 functional GI disorders, and 11\u00a0gastroparesis. Children with poor TPP had longer GE\u2010T<jats:sub>1\/2<\/jats:sub> (113.0 vs 66.5\u00a0min, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.028), higher RR of the whole stomach and fundus at 1\u00a0h (79.5% vs 63.5%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.038; 60.0% vs 41.0%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.022, respectively) and 2\u00a0h (51.0% vs 10.5%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.005; 36.0% vs 6.5%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.004, respectively). The pre\u2010prandial antral amplitude of contractions inversely correlated with GE\u2010T<jats:sub>1\/2<\/jats:sub>, RR of the whole stomach, and fundus at 2\u00a0h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TPP during phase III of the MMC correlated with gastric emptying of liquid and its assessment on ADM might predict abnormalities in postprandial gastric function.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14334","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T13:52:45Z","timestamp":1646661165000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Transpyloric propagation and liquid gastric emptying in children with foregut dysmotility"],"prefix":"10.1111","volume":"34","author":[{"given":"Ilaria","family":"Rochira","sequence":"first","affiliation":[{"name":"Neurogastroenterology &amp; Motility Unit Gastroenterology Department Great Ormond Street Hospital for Children  London UK"},{"name":"Department of Paediatrics Children\u2019s Hospital ASST Spedali Civili University of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4750-4973","authenticated-orcid":false,"given":"Atchariya","family":"Chanpong","sequence":"additional","affiliation":[{"name":"Neurogastroenterology &amp; 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