{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:14:09Z","timestamp":1793826849655,"version":"4.6.1"},"reference-count":115,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["RO1DK78924"],"award-info":[{"award-number":["RO1DK78924"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anorectal manometry (ARM) comprehensively assesses anorectal sensorimotor functions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This review examines the indications, techniques, interpretation, strengths, and weaknesses of high\u2010resolution ARM (HR\u2010ARM), 3\u2010dimensional high\u2010resolution anorectal manometry (3D\u2010HR\u2010ARM), and portable ARM, and other assessments (i.e., rectal sensation and rectal balloon expulsion test) that are performed alongside manometry. It is based on a literature search of articles related to ARM in adults. HR\u2010ARM and 3D\u2010HR\u2010ARM are useful for diagnosing defecatory disorders (DD), to identify anorectal sensorimotor dysfunction and guide management in patients with fecal incontinence (FI), constipation, megacolon, and megarectum; and to screen for anorectal structural (e.g., rectal intussusception) abnormalities. The rectal balloon expulsion test is a useful, low\u2010cost, radiation\u2010free, outpatient assessment tool for impaired evacuation that is performed and interpreted in conjunction with ARM. The anorectal function tests should be interpreted with reference to age\u2010 and sex\u2010matched normal values, clinical features, and results of other tests. A larger database of technique\u2010specific normal values and newer paradigms of analyzing anorectal pressure profiles will increase the precision and diagnostic utility of HR\u2010ARM for identifying abnormal mechanisms of defecation and continence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.14335","type":"journal-article","created":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T13:09:18Z","timestamp":1645967358000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["Review of the indications, methods, and clinical utility of anorectal manometry and the rectal balloon expulsion test"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7644-0390","authenticated-orcid":false,"given":"Adil E.","family":"Bharucha","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5043-9666","authenticated-orcid":false,"given":"Guido","family":"Basilisco","sequence":"additional","affiliation":[{"name":"UO Gastroenterologia Fondazione IRCCS C\u00e0 Granda Ospedale Maggiore Policlinico  Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Malcolm","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Royal North Shore Hospital and University of Sydney  Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Digestive Disease Center Soonchunhyang University Seoul Hospital  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew B.","family":"Hoy","sequence":"additional","affiliation":[{"name":"Mayo Medical Library Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7997-1533","authenticated-orcid":false,"given":"S. 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