{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:52:57Z","timestamp":1792637577252,"version":"4.5.0"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Satisfaction with current treatment options for irritable bowel syndrome with constipation (IBS\u2010C) is low, with many patients turning to complementary treatments. Tai Chi is a mind\u2013body medicine practice with proven efficacy in other functional disorders. As a proof\u2010of\u2010concept, we tested the feasibility and preliminary clinical outcomes associated with a Tai Chi program designed for IBS\u2010C.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 27 IBS\u2010C patients participated in a single\u2010arm trial of 8 sessions of Tai Chi delivered weekly over 7\u2009weeks via live videoconferencing in group format. Clinical improvement was assessed via change in IBS Symptom Severity Score (IBS\u2010SSS) from baseline to 4\u2009weeks posttreatment (week 11) with secondary outcomes exploring symptom ratings, IBS\u2010related quality of life (IBS\u2010QOL), GI\u2010specific anxiety, abdominal distention, and psychological factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Despite substantial dropout (<jats:italic>n<\/jats:italic>\u00a0=\u00a07; 26%), the treatment protocol had moderate to excellent feasibility for other criteria. Treatment satisfaction was excellent. Exit interviews confirmed high satisfaction with the program among completers, but a high burden of data collection was noted. One participant experienced an adverse event (mild, exacerbation of sciatica). There was a significant improvement in intra\u2010individual IBS\u2010SSS between baseline and posttreatment (average change \u221266.5, 95% CI \u2212118.6 to \u221214.3, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.01). Secondary outcomes were notable for improvements in other IBS symptom scoring measures, IBS\u2010QOL, measured abdominal diameter, and leg strength.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Inferences<\/jats:title><jats:p>Our data provide preliminary evidence of the feasibility of a Tai Chi intervention for IBS\u2010C, show promise for improving outcomes, and identify more streamlined data collection as an area for further program improvement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14429","type":"journal-article","created":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T12:51:05Z","timestamp":1657803065000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Virtual Tai Chi program for patients with irritable bowel syndrome with constipation: Proof\u2010of\u2010concept feasibility trial"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4925-4290","authenticated-orcid":false,"given":"Kyle","family":"Staller","sequence":"first","affiliation":[{"name":"Division of Gastroenterology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Center for Neurointestinal Health Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Paz","sequence":"additional","affiliation":[{"name":"Institute of Health Professions Massachusetts General Hospital  Charlestown Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramel","family":"Rones","sequence":"additional","affiliation":[{"name":"Mind Body Consultant, Tufts Medical Center, Mass General Hospital Dana Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Macklin","sequence":"additional","affiliation":[{"name":"Biostatistics Center Massachusetts General Hospital and Harvard Medical School Boston  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Garcia\u2010Fischer","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Center for Neurointestinal Health Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2059-3256","authenticated-orcid":false,"given":"Helen Burton","family":"Murray","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Center for Neurointestinal Health Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braden","family":"Kuo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Center for Neurointestinal Health Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.02.029"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.10.036"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.108"},{"issue":"9","key":"e_1_2_10_5_1","first-page":"536","article-title":"Complementary and alternative medicine for the management of irritable bowel syndrome","volume":"14","author":"Nguyen L","year":"2018","journal-title":"Gastroenterol 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