{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:31:31Z","timestamp":1791318691799,"version":"4.3.1"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100010566","name":"Rome Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010566","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although the Rome IV criteria are the most recent criteria to diagnose irritable bowel syndrome (IBS), their sensitivity has been shown to be low in Chinese and Western populations. There are scanty data comparing the Rome III and Rome IV criteria in diagnosis of IBS in the Indian and Bangladeshi populations where abdominal pain, an essential component of diagnosis of IBS by the Rome IV criteria, is less in frequency and of lower severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed the Indian and Bangladeshi data from the Rome Global Epidemiology Study to compare diagnostic sensitivity of the Rome III and Rome IV criteria for IBS, internal shifts in diagnostic categories of disorders of gut\u2013brain interaction (DGBI), the severity of IBS diagnosed by the Rome III and Rome IV criteria, and consultation patterns in these populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The Rome IV criteria were less sensitive than the Rome III criteria to diagnose IBS in these populations, and the subjects with Rome III IBS shifted internally to other DGBI when the Rome IV criteria were applied. Moreover, Rome IV IBS subjects had greater symptom severity than the Rome III IBS. A third of people fulfilling diagnostic criteria for IBS consulted doctors, and those diagnosed using Rome IV criteria, those with higher anxiety and depression symptom score, lower global physical health score, and greater IBS symptom severity score had greater correlation coefficients with doctors' consultation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Inferences<\/jats:title><jats:p>The Rome IV diagnostic criteria for IBS are less sensitive than the Rome III criteria in Indian and Bangladesh communities. Application of the Rome IV criteria to people who meet the Rome III IBS criteria selects a subgroup of people with greater severity of symptoms, and hence, Rome IV IBS is more strongly associated with physician consultation. These findings may have important bearing in future iterations of the Rome criteria for a broader global applicability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14579","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T15:24:16Z","timestamp":1680535456000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Comparisons of the Rome <scp>III<\/scp> and Rome <scp>IV<\/scp> criteria for diagnosis of irritable bowel syndrome in Indian and Bangladeshi communities and internal shifts in the diagnostic categories of bowel disorders of gut\u2013brain interactions"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0221-8495","authenticated-orcid":false,"given":"Uday C.","family":"Ghoshal","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow 226014 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9713-2223","authenticated-orcid":false,"given":"M. Masudur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Sheikh Russel National Gastroliver Institute and Hospital  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitesh","family":"Pratap","sequence":"additional","affiliation":[{"name":"KIMS Hospitals  Secunderabad Hyderabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asha","family":"Misra","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow 226014 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shafiqul Alam","family":"Sarker","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research (icddr,b)  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmud","family":"Hasan","sequence":"additional","affiliation":[{"name":"Gastroliver Foundation  Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrikant I.","family":"Bangdiwala","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence and Impact McMaster University  Hamilton Ontario Canada"},{"name":"Population Health Research Institute McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olafur S.","family":"Palsson","sequence":"additional","affiliation":[{"name":"Center for Functional Gastrointestinal and Motility Disorders University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7634-3689","authenticated-orcid":false,"given":"Ami D.","family":"Sperber","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.04.014"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.02.029"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-311240"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2010.12.013"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2002.01290.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.032"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.031"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm16214"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i37.6788"},{"key":"e_1_2_10_11_1","first-page":"22","article-title":"Epidemiological and clinical profile of irritable bowel syndrome in India: reportof the Indian Society of Gastroenterology Task Force","volume":"27","author":"Ghoshal UC","year":"2008","journal-title":"Indian J Gastroenterol"},{"key":"e_1_2_10_12_1","first-page":"133","article-title":"Can pain be an optional clinical criterion for irritable bowel syndrome","volume":"1","author":"Venkataraman J","year":"2007","journal-title":"Hungarian Med J"},{"key":"e_1_2_10_13_1","first-page":"15","article-title":"Clinical profile of irritable bowel syndrome","volume":"4","author":"Kapoor KK","year":"1985","journal-title":"Indian J Gastroenterol"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-013-0365-7"},{"key":"e_1_2_10_15_1","first-page":"1","article-title":"Comparative prevalence of Iritable bowel Syndrom (IBS) using multiple diagnostic criteria","volume":"21","author":"Perveen I","year":"2010","journal-title":"Bangladesh J Med"},{"key":"e_1_2_10_16_1","first-page":"108","article-title":"Primary care consultation predictors in men and women: a cohort study","volume":"55","author":"Kapur N","year":"2005","journal-title":"Br J Gen Pract"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13465"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03760.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.56099"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12402"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.05.042"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm14045"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13642"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2019.1698650"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.05.037"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12975"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.12.021"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41395-018-0074-z"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13189"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2005.02.008"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01498.x"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.02928.x"}],"container-title":["Neurogastroenterology &amp; Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.14579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T00:30:47Z","timestamp":1692664247000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.14579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,3]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/nmo.14579"],"URL":"https:\/\/doi.org\/10.1111\/nmo.14579","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"value":"1350-1925","type":"print"},{"value":"1365-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,3]]},"assertion":[{"value":"2023-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14579"}}