{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T17:43:59Z","timestamp":1785519839606,"version":"3.56.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Data for Spain from the Rome Foundation Global Epidemiology Study on the disorders of gut\u2013brain interaction (DGBI) were used to assess the national and regional prevalence of all 22 DGBI, the percentage of respondents meeting diagnostic criteria for at least one DGBI, and the impact on burden of disease in our country.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected through an anonymous, nationwide, and secure Internet survey with multiple built\u2010in quality\u2010assurance techniques that included the Rome IV diagnostic questionnaire and an in\u2010depth supplemental questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The survey was completed by 2072 adult Spanish participants (50.2% female) with a mean age of 45.67\u2009\u00b1\u200915.44\u2009years with a good representative national distribution. 43.6% (41.5%\u201345.8%) met diagnostic criteria for at least one DGBI, with 8.2% for any esophageal disorder, 12.1% for any gastroduodenal disorder, 30.1% for any bowel disorder, and 11.5% for any anorectal disorder. Functional constipation was the most prevalent DGBI in Spain (12.8%). We found that <jats:italic>proctalgia fugax<\/jats:italic> (9.3%), unspecified bowel disorders (10.8%), and functional dysphagia (5.6%) showed unexplained high rates in our country. DGBI rates were higher for women. Having any DGBI was negatively associated with psychosocial variables (including quality of life, somatization, and concern about digestive problems), and associated with increased healthcare utilization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>We provide the first comprehensive data on the prevalence and burden of all DGBI in Spain using the Rome IV criteria. The enormous burden of DGBI in Spain highlights the need for specialized training and future research.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14582","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T15:30:25Z","timestamp":1680535825000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and description of disorders of <scp>gut\u2013brain<\/scp> interaction in Spain according to the results of the Rome Foundation Global Epidemiology Study"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0299-4216","authenticated-orcid":false,"given":"Joel","family":"Flores\u2010Arriaga","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Vall d'Hebron Hospital Universitari Vall d'Hebron Barcelona Hospital Campus  Barcelona 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