{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:34:32Z","timestamp":1792978472234,"version":"4.5.0"},"reference-count":64,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The barium swallow is a commonly performed investigation, though recent decades have seen major advances in other esophageal diagnostic modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose of this review is to clarify the rationale for components of the barium swallow protocol, provide guidance on interpretation of findings, and describe the current role of the barium swallow in the diagnostic paradigm for esophageal dysphagia in relation to other esophageal investigations. The barium swallow protocol, interpretation, and reporting terminology are subjective and non\u2010standardized. Common reporting terminology and an approach to their interpretation are provided. A <jats:italic>timed<\/jats:italic> barium swallow (TBS) protocol provides more standardized assessment of esophageal emptying but does not evaluate peristalsis. Barium swallow may have higher sensitivity than endoscopy for detecting subtle strictures. Barium swallow has lower overall accuracy than high\u2010resolution manometry for diagnosing achalasia but can help secure the diagnosis in cases of equivocal manometry. TBS has an established role in objective assessment of therapeutic response in achalasia and helps identify the cause of symptom relapse. Barium swallow has a role in the evaluating manometric esophagogastric junction outflow obstruction, in some cases helping to identify where it represents an achalasia\u2010like syndrome. Barium swallow should be performed in dysphagia following bariatric or anti\u2010reflux surgery, to assess for both structural and functional postsurgical abnormality. Barium swallow remains a useful investigation in esophageal dysphagia, though its role has evolved due to advancements in other diagnostics. Current evidence\u2010based guidance regarding its strengths, weaknesses, and current role are described in this review.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14605","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T14:49:03Z","timestamp":1682606943000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["How to effectively use and interpret the barium swallow: Current role in esophageal dysphagia"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3145-1050","authenticated-orcid":false,"given":"Santosh","family":"Sanagapalli","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology St. Vincent's Hospital Sydney  Darlinghurst Australia"},{"name":"School of Clinical Medicine St. Vincent's Healthcare Campus University of New South Wales  Sydney 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