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FI, IBS, and constipation were evaluated with the Rome IV criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The prevalence of FI was 10.5% (<jats:italic>n<\/jats:italic>\u2009=\u2009329) in the non\u2010comorbidity group. After multivariable logistic regression analysis, IBS (odds ratio [OR]: 12.55, 95% confidence interval [CI]: 9.06\u201317.36) and constipation (OR: 4.38, 95% CI: 3.27\u20135.85) were the most significant factors contributing to FI. Based on this finding, 106\/329 (32.2%) had IBS\u2010associated FI, 119\/329 (36.2%) had constipation\u2010associated FI, and 104\/329 (31.6%) had isolated FI. Among the 329 FI respondents, there was a high prevalence of IBS and constipation\u2010related symptoms, including abdominal pain (81.5%) and abdominal bloating (77.8%) for IBS and straining during defecation (75.4%), incomplete defecation (72.3%), defecation blockage (63.2%), anal pain during defecation (59.3%), and hard stools (24%) for constipation. The patients with IBS\u2010associated FI asked for specialists' help less frequently than those with isolated FI. Interestingly, among the patients with constipation\u2010associated FI, 56.3% used anti\u2010diarrhea medicine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Inferences<\/jats:title><jats:p>The prevalence of IBS\u2010associated FI, constipation\u2010associated FI, and isolated FI is comparably high. It is important to diagnose and target the cause of FI to provide personalized and cause\u2010targeting care instead of treating only the FI symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14633","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T09:29:26Z","timestamp":1688981366000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Co\u2010occurrence of fecal incontinence with constipation or irritable bowel syndrome indicates the need for personalized treatment"],"prefix":"10.1111","volume":"35","author":[{"given":"Ge","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Surgery, Anorectal Physiology Laboratory, University of Groningen University Medical Center Groningen  Groningen The Netherlands"},{"name":"Department of Colorectal Surgery, Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Trzpis","sequence":"additional","affiliation":[{"name":"Department of Surgery, Anorectal Physiology Laboratory, University of Groningen University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibo","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianhua","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M. 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