{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:29:36Z","timestamp":1789655376108,"version":"4.0.1"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Effect of biofeedback on improving anorectal manometric parameters in incomplete spinal cord injury is unknown. A short\u2010term biofeedback program investigated any effect on anorectal manometric parameters without correlation to bowel symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective uncontrolled interventional study comprised three study subject groups,\n                      <jats:italic>Group 1<\/jats:italic>\n                      : sensory\/motor\u2010complete American Spinal Injury Association Impairment Scale (AIS) A SCI (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200913);\u2009\n                      <jats:italic>Group 2<\/jats:italic>\n                      (\n                      <jats:italic>biofeedback group<\/jats:italic>\n                      ): sensory incomplete AIS B SCI (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200917) (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093), and motor\u2010incomplete AIS C SCI (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20098), and AIS D SCI (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096); and\n                      <jats:italic>Group 3<\/jats:italic>\n                      : able\u2010bodied (AB) controls (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200912). High\u2010resolution anorectal manometry (HR\u2010ARM) was applied to establish baseline characteristics in all subjects for anorectal pressure, volume, length of pressure zones, and duration of sphincter squeeze pressure. SCI participants with motor\u2010incomplete SCI were enrolled in pelvic floor\/anal sphincter bowel biofeedback training (2\u2009\u00d7\u20096\u2010week training periods comprised of two training sessions per week for 30\u201345\u2009min per session). HR\u2010ARM was also performed after each of the 6\u2010week periods of biofeedback training.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared to motor\u2010complete or motor\u2010incomplete SCI participants, AB subjects had higher mean intra\u2010rectal pressure, maximal sphincteric pressure, residual anal pressure, recto\u2010anal pressure gradient, and duration of squeeze (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 for each of the endpoints). No significant difference was evident at baseline between the motor\u2010complete and motor\u2010incomplete SCI groups. In motor\u2010incomplete SCI subjects, the pelvic floor\/anal sphincter biofeedback protocol failed to improve HR\u2010ARM parameters.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Biofeedback training program did not improve anal manometric parameters in subjects with motor\u2010incomplete or sensory\u2010incomplete SCI. Biofeedback did not change physiology, and\u2009its effects on symptoms are unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Inferences<\/jats:title>\n                    <jats:p>Utility of biofeedback is limited in patients with incomplete spinal cord injury in terms of improving HR\u2010ARM parameters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.14667","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T03:35:41Z","timestamp":1695612941000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Lack of improvement in anorectal manometry parameters after implementation of a pelvic floor\/anal sphincter biofeedback in persons with motor\u2010incomplete spinal cord injury"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6191-0524","authenticated-orcid":false,"given":"Mark M.","family":"Aloysius","sequence":"first","affiliation":[{"name":"Department of Medicine The Wright Center for Graduate Medical Education  Scranton Pennsylvania USA"},{"name":"Department of Medicine Geisinger Commonwealth School of Medicine  Scranton Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Korsten","sequence":"additional","affiliation":[{"name":"National Center for Medical Consequences of Spinal Cord Injury James J Peters VA Medical Center  Bronx New York USA"},{"name":"Medical Service James J Peters VA Medical Center  Bronx New York USA"},{"name":"Department of Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"Department of Rehabilitation Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Radulovic","sequence":"additional","affiliation":[{"name":"National Center for Medical Consequences of Spinal Cord Injury James J Peters VA Medical Center  Bronx New York USA"},{"name":"Medical Service James J Peters VA Medical Center  Bronx New York USA"},{"name":"Department of Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"Department of Rehabilitation Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamaldeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Medicine College of Medicine  Tucson Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian L.","family":"Lyons","sequence":"additional","affiliation":[{"name":"National Center for Medical Consequences of Spinal Cord Injury James J Peters VA Medical Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tradd","family":"Cummings","sequence":"additional","affiliation":[{"name":"Bristol Myer's Squibb  Stroudsburg Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Hobson","sequence":"additional","affiliation":[{"name":"National Center for Medical Consequences of Spinal Cord Injury James J Peters VA Medical Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Kahal","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M.","family":"Spungen","sequence":"additional","affiliation":[{"name":"National Center for Medical Consequences of Spinal Cord Injury James J Peters VA Medical Center  Bronx New York USA"},{"name":"Department of Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"Department of Rehabilitation Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Bauman","sequence":"additional","affiliation":[{"name":"National Center for Medical Consequences of Spinal Cord Injury James J Peters VA Medical Center  Bronx New York USA"},{"name":"Medical Service James J Peters VA Medical Center  Bronx New York USA"},{"name":"Department of Medicine The Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"Department of Rehabilitation Medicine The Icahn School of Medicine at Mount Sinai  New York New York 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