{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:01:29Z","timestamp":1790744489415,"version":"4.1.0"},"reference-count":118,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic intestinal pseudo\u2010obstruction is a rare and heterogeneous syndrome characterized by recurrent symptoms of intestinal obstruction with radiological features of dilated small or large intestine with air\/fluid levels in the absence of any mechanical occlusive lesion. Several diseases may be associated with chronic intestinal pseudo\u2010obstruction and in these cases, the prognosis and treatment are related to the underlying disease. Also, in its \u201cprimary or idiopathic\u201d form, two subgroups of patients should be determined as they require a more specific therapeutic approach: patients whose chronic intestinal pseudo\u2010obstruction is due to sporadic autoimmune\/inflammatory mechanisms and patients whose neuromuscular changes are genetically determined. In a context of a widely heterogeneous adult population presenting chronic intestinal pseudo\u2010obstruction, this review aims to summarize a practical diagnostic workup for identifying definite subgroups of patients who might benefit from more specific treatments, based on the etiology of their underlying condition.<\/jats:p>","DOI":"10.1111\/nmo.14715","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T23:57:05Z","timestamp":1700870225000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Chronic intestinal pseudo\u2010obstruction in adults: A practical guide to identify patient subgroups that are suitable for more specific treatments"],"prefix":"10.1111","volume":"36","author":[{"given":"Guido","family":"Basilisco","sequence":"first","affiliation":[{"name":"Gastroenterology and Endoscopic Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5098-8534","authenticated-orcid":false,"given":"Margherita","family":"Marchi","sequence":"additional","affiliation":[{"name":"Neuroalgology Unit Fondazione IRCCS Istituto Neurologico \u201cCarlo Besta\u201d  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Coletta","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopic Unit Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,22]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.41.5.675"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000630"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000001047"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12945"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13937"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20120173"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520902840806"},{"key":"e_1_2_16_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.01.020"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.09.008"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520902839642"},{"key":"e_1_2_16_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2019.101635"},{"key":"e_1_2_16_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.17.s1.7.x"},{"key":"e_1_2_16_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14438"},{"key":"e_1_2_16_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.57"},{"key":"e_1_2_16_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12735"},{"key":"e_1_2_16_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14062"},{"key":"e_1_2_16_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2007.03.001"},{"key":"e_1_2_16_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(94)90692-0"},{"key":"e_1_2_16_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13611"},{"key":"e_1_2_16_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.05.048"},{"key":"e_1_2_16_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1365142"},{"key":"e_1_2_16_23_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00066.2021"},{"key":"e_1_2_16_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00675-5"},{"key":"e_1_2_16_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2019-317085"},{"key":"e_1_2_16_26_1","doi-asserted-by":"publisher","DOI":"10.1586\/17474124.2014.940317"},{"key":"e_1_2_16_27_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2472070182"},{"key":"e_1_2_16_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-010-2694-2"},{"key":"e_1_2_16_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0612-z"},{"key":"e_1_2_16_30_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2012-0220-OA"},{"key":"e_1_2_16_31_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1706594"},{"key":"e_1_2_16_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2007.053959"},{"key":"e_1_2_16_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-013-3361-1"},{"key":"e_1_2_16_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20944"},{"key":"e_1_2_16_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640615611630"},{"key":"e_1_2_16_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14643"},{"key":"e_1_2_16_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jimd.12300"},{"key":"e_1_2_16_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom12121849"},{"key":"e_1_2_16_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-018-0101-0"},{"key":"e_1_2_16_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.29.11.791"},{"key":"e_1_2_16_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(88)80034-9"},{"key":"e_1_2_16_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(86)90948-0"},{"key":"e_1_2_16_43_1","first-page":"1640","article-title":"Congenital muscular dystrophy and congenital myopathy","volume":"25","author":"Butterfield RJ","year":"2019","journal-title":"Continuum (Minneap Minn)"},{"key":"e_1_2_16_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01818993"},{"key":"e_1_2_16_45_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI14377"},{"key":"e_1_2_16_46_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200009213431204"},{"key":"e_1_2_16_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-018-1477-8"},{"key":"e_1_2_16_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00382-6"},{"key":"e_1_2_16_49_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.7547"},{"key":"e_1_2_16_50_1","doi-asserted-by":"publisher","DOI":"10.1159\/000503897"},{"key":"e_1_2_16_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-018-0909-6"},{"key":"e_1_2_16_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2016.11.005"},{"key":"e_1_2_16_53_1","doi-asserted-by":"publisher","DOI":"10.14309\/crj.2013.10"},{"key":"e_1_2_16_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2017.09.011"},{"key":"e_1_2_16_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.43.1.117"},{"key":"e_1_2_16_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2013.01.002"},{"key":"e_1_2_16_57_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9510316"},{"key":"e_1_2_16_58_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1312921"},{"key":"e_1_2_16_59_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000899"},{"key":"e_1_2_16_60_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm14118"},{"key":"e_1_2_16_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2018.e00425"},{"key":"e_1_2_16_62_1","first-page":"25","article-title":"Diagnosis and clinical management of Chagas disease: an increasing challenge in non\u2010endemic areas","volume":"13","author":"Su\u00e1rez C","year":"2022","journal-title":"Res Rep Trop Med"},{"key":"e_1_2_16_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(91)90593-A"},{"key":"e_1_2_16_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10577-8"},{"key":"e_1_2_16_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.6.1138"},{"key":"e_1_2_16_66_1","doi-asserted-by":"publisher","DOI":"10.1159\/000117295"},{"key":"e_1_2_16_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(97)70151-3"},{"key":"e_1_2_16_68_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.45.5.775"},{"key":"e_1_2_16_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9270(02)04359-9"},{"key":"e_1_2_16_70_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200504000-00010"},{"key":"e_1_2_16_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gcb.2007.12.010"},{"key":"e_1_2_16_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-008-9787-y"},{"key":"e_1_2_16_73_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520701396216"},{"key":"e_1_2_16_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-0838-9"},{"key":"e_1_2_16_75_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001265"},{"key":"e_1_2_16_76_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.92396"},{"key":"e_1_2_16_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2007.01033.x"},{"key":"e_1_2_16_78_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.071811"},{"key":"e_1_2_16_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(85)90587-6"},{"key":"e_1_2_16_80_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.148296"},{"key":"e_1_2_16_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13153"},{"key":"e_1_2_16_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2008.01099.x"},{"key":"e_1_2_16_83_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1391781"},{"key":"e_1_2_16_84_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.200444"},{"key":"e_1_2_16_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0527-y"},{"key":"e_1_2_16_86_1","unstructured":"Online Mendelian Inheritance in Man OMIM\u00ae. McKusick\u2010Nathans Institute of Genetic Medicine Johns Hopkins University;2023.https:\/\/omim.org\/"},{"key":"e_1_2_16_87_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001982"},{"key":"e_1_2_16_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13371"},{"key":"e_1_2_16_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.08707.x"},{"key":"e_1_2_16_90_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004258"},{"key":"e_1_2_16_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.08.051"},{"key":"e_1_2_16_92_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.08.045"},{"key":"e_1_2_16_93_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm20243"},{"key":"e_1_2_16_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2015.275"},{"key":"e_1_2_16_95_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.23960"},{"key":"e_1_2_16_96_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.12.034"},{"key":"e_1_2_16_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3113"},{"key":"e_1_2_16_98_1","doi-asserted-by":"publisher","DOI":"10.1086\/513321"},{"key":"e_1_2_16_99_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181f0ae47"},{"key":"e_1_2_16_100_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.23355"},{"key":"e_1_2_16_101_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddac199"},{"key":"e_1_2_16_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.23986"},{"key":"e_1_2_16_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2017.05.011"},{"key":"e_1_2_16_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2017.10.008"},{"key":"e_1_2_16_105_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14335"},{"key":"e_1_2_16_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01880_13.x"},{"key":"e_1_2_16_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.01838.x"},{"key":"e_1_2_16_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04907.x"},{"key":"e_1_2_16_109_1","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2013.46.5.591"},{"key":"e_1_2_16_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13127"},{"key":"e_1_2_16_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2111-x"},{"key":"e_1_2_16_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.07.002"},{"key":"e_1_2_16_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00436.x"},{"key":"e_1_2_16_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2013.06.014"},{"key":"e_1_2_16_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12391"},{"key":"e_1_2_16_116_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.4.479"},{"key":"e_1_2_16_117_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.901824"},{"key":"e_1_2_16_118_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.11.048"},{"key":"e_1_2_16_119_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.03.014"}],"container-title":["Neurogastroenterology &amp; Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.14715","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T04:47:40Z","timestamp":1704948460000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.14715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,22]]},"references-count":118,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/nmo.14715"],"URL":"https:\/\/doi.org\/10.1111\/nmo.14715","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"value":"1350-1925","type":"print"},{"value":"1365-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,22]]},"assertion":[{"value":"2023-07-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14715"}}