{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T16:38:51Z","timestamp":1783183131109,"version":"3.54.6"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:00:00Z","timestamp":1701907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009193","name":"Marsden Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009193","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Despite evidence that slow\u2010wave dysrhythmia in the stomach is associated with clinical conditions such as gastroparesis and functional dyspepsia, there is still no widely available device for long\u2010term monitoring of gastric electrical signals. Actionable biomarkers of gastrointestinal health are critically needed, and an implantable slow\u2010wave monitoring device could aid in the establishment of causal relationships between symptoms and gastric electrophysiology. Recent developments in the area of wireless implantable gastric monitors demonstrate potential, but additional work and validation are required before this potential can be realized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We hypothesized that translating an existing implantable cardiac monitoring device, the Reveal LINQ\u2122 (Medtronic), would present a more immediate solution. Following ethical approval and laparotomy in anesthetized pigs (<jats:italic>n<\/jats:italic>\u2009=\u20097), a Reveal LINQ was placed on the serosal surface of the stomach, immediately adjacent to a validated flexible\u2010printed\u2010circuit (FPC) electrical mapping array. Data were recorded for periods of 7.5\u2009min, and the resultant signal characteristics from the FPC array and Reveal LINQ were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>The Reveal LINQ device recorded slow waves in 6\/7 subjects with a comparable period (<jats:italic>p<\/jats:italic>\u2009=\u20090.69), signal\u2010to\u2010noise ratio (<jats:italic>p<\/jats:italic>\u2009=\u20090.58), and downstroke width (<jats:italic>p<\/jats:italic>\u2009=\u20090.98) to the FPC, but with reduced amplitude (<jats:italic>p<\/jats:italic>\u2009=\u20090.024). Qualitatively, the Reveal LINQ slow\u2010wave signal lacked the prolonged repolarization phase present in the FPC signals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>These findings suggest that existing cardiac monitors may offer an efficient solution for the long\u2010term monitoring of slow waves. Translation toward implantation now awaits.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14723","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T06:21:53Z","timestamp":1702016513000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Translation of an existing implantable cardiac monitoring device for measurement of gastric electrical slow\u2010wave activity"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6674-6548","authenticated-orcid":false,"given":"Jarrah M.","family":"Dowrick","sequence":"first","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5429-3393","authenticated-orcid":false,"given":"Lisa","family":"Jungbauer\u00a0Nikolas","sequence":"additional","affiliation":[{"name":"Pelvic Health Medtronic PLC  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6072-4455","authenticated-orcid":false,"given":"Sarah J.","family":"Offutt","sequence":"additional","affiliation":[{"name":"Pelvic Health Medtronic PLC  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Tremain","sequence":"additional","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6307-5240","authenticated-orcid":false,"given":"Jonathan C.","family":"Erickson","sequence":"additional","affiliation":[{"name":"Department of Physics and Engineering Washington and Lee University  Lexington Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1610-3787","authenticated-orcid":false,"given":"Timothy R.","family":"Angeli\u2010Gordon","sequence":"additional","affiliation":[{"name":"Auckland Bioengineering Institute, University of Auckland  Auckland New Zealand"},{"name":"Department of Surgery University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.254292"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1922.02640680020008"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1109\/RBME.2018.2867555"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-009-9654-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.04.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.05.036"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abq3544"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14048"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14556"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-020-06663-y"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2019.22.6.518"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-320325"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/33\/6\/N29"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12515"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1109\/JETCAS.2018.2812105"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6579\/ab0668"},{"key":"e_1_2_11_18_1","doi-asserted-by":"crossref","unstructured":"IbrahimA KianiM FarajidavarA.A 64\u2010channel wireless implantable system\u2010on\u2010chip for gastric electrical\u2010wave recording. 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