{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T22:42:57Z","timestamp":1781649777777,"version":"3.54.5"},"reference-count":42,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T00:00:00Z","timestamp":1716681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The association between upper gastrointestinal symptoms and delayed gastric emptying (GE) shows conflicting results. This study aimed to assess whether the symptoms of the Gastroparesis Cardinal Symptom Index (GCSI) and\/or the scores were associated with the result of GE tests and whether they could predict delayed GE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients referred for suspected gastroparesis (GP) were included in a prospective database. Demographical data, medical history, and symptoms of the GCSI score were collected for each patient. A GE scintigraphy was then performed with a 4\u2010hour recording. Delayed GE was defined as a retention rate \u2265\u200910% at 4\u2009h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 243 patients included in this study, 110 patients (45%) had delayed GE. The mean age (49.9 vs. 41.3\u2009years; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and weight loss (9.4\u2009kg vs. 5.6\u2009kg; <jats:italic>p<\/jats:italic>\u2009=\u20090.025) were significantly higher in patients with delayed GE. Patients with diabetes or a history of surgery had a higher prevalence of delayed GE (60% and 78%, respectively) than patients without comorbidity (17%; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The GCSI score was higher in patients with delayed GE (3.06 vs. 2.80; <jats:italic>p<\/jats:italic>\u2009=\u20090.045), but no threshold was clinically relevant to discriminate between patients with normal and delayed GE. Only vomiting severity was significantly higher in patients with delayed GE (2.19 vs. 1.57; <jats:italic>p<\/jats:italic>\u2009=\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>GE testing should be considered when there are symptoms such as a higher weight loss, comorbidities (diabetes, and history of surgery associated with GP), and the presence of vomiting. Other symptoms and the GCSI score are not useful in predicting delayed GE.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14821","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T06:29:38Z","timestamp":1716791378000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Symptoms from the Gastroparesis Cardinal Symptom Index and clinical factors associated with delayed gastric emptying in patients with suspected gastroparesis"],"prefix":"10.1111","volume":"36","author":[{"given":"Claire","family":"Sabat","sequence":"first","affiliation":[{"name":"D\u00e9partement d'H\u00e9pato Gastro Ent\u00e9rologie AP\u2010HP Nord, H\u00f4pital Louis Mourier  Colombes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachida","family":"Lebtahi","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine nucl\u00e9aire, AP\u2010HP Nord, Universit\u00e9 Paris Cit\u00e9 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