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Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and whose afferents are distributed throughout the different layers of the digestive wall. The vagus nerve is a key element of the autonomic nervous system, involved in the stress response, at the interface of the microbiota\u2010gut\u2010brain axis, has anti\u2010inflammatory and prokinetic properties, modulates intestinal permeability, and has a significant capacity of plasticity and regeneration. Targeting these properties of the vagus nerve, with vagus nerve stimulation (or non\u2010stimulation\/ pharmacological methods), could be of interest in the therapeutic management of enteric neuropathies.<\/jats:p>","DOI":"10.1111\/nmo.14842","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T05:48:13Z","timestamp":1718344093000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Enteric neuropathy and the vagus nerve: Therapeutic implications"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1858-8941","authenticated-orcid":false,"given":"Bruno","family":"Bonaz","sequence":"first","affiliation":[{"name":"Grenoble Institut des Neurosciences Universit\u00e9 Grenoble Alpes\u2010Facult\u00e9 de M\u00e9decine  Grenoble 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