{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:45:57Z","timestamp":1791852357308,"version":"4.3.4"},"reference-count":59,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although swallowing impairment is prevalent following lung transplantation, baseline respiratory and swallowing characteristics are often overlooked. Respiratory disease processes may predispose lung transplant candidates to altered respiratory\u2010swallow patterning and swallowing impairment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study included patients referred for a Modified Barium Swallow Study during lung transplant evaluation. Swallowing impairment was measured using the Modified Barium Swallow Impairment Profile and Penetration\u2010Aspiration Scale. Respiratory plethysmographic signals synchronized with videofluoroscopy were analyzed to determine phase patterning, pause duration, and rate. Mixed\u2010effects logistic regression was used to identify linkages between respiratory and swallowing measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Fifty patients were included and demonstrated delayed swallow initiation (49\/50), oral residue (37\/50), incomplete pharyngoesophageal segment opening (35\/50), and esophageal retention (43\/50). Airway invasion occurred infrequently (10\/50). Atypical respiratory patterning was significantly associated with impairment in pharyngeal swallow initiation (OR [95% CI]\u2009=\u20091.76 [1.16, 2.68], <jats:italic>p<\/jats:italic>\u2009=\u20090.009), laryngeal elevation (OR [95% CI]\u2009=\u20091.45 [1.01, 2.07], <jats:italic>p<\/jats:italic>\u2009=\u20090.044), and laryngeal vestibular closure (OR [95% CI]\u2009=\u20092.57 [1.48, 4.46], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Increased pause duration was associated with impaired initiation (OR [95% CI]\u2009=\u20092.24 [1.20, 4.16], <jats:italic>p<\/jats:italic>\u2009=\u20090.011), laryngeal elevation (OR [95% CI]\u2009=\u20091.18 [1.03, 1.36], <jats:italic>p<\/jats:italic>\u2009=\u20090.018), laryngeal closure (OR [95% CI]\u2009=\u20091.28 [1.9, 1.50], <jats:italic>p<\/jats:italic>\u2009=\u20090.003), and tongue base retraction (OR [95% CI]\u2009=\u20091.33 [1.13, 1.56], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions &amp; Inferences<\/jats:title><jats:p>Patients undergoing evaluation for lung transplant demonstrated impaired swallowing and phase patterning. Preliminary findings implicate the need for further evaluation of respiratory\u2010swallow coordination and its potential role in swallowing impairment before and after lung transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14912","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T06:40:25Z","timestamp":1725345625000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Respiratory\u2010swallow patterning and oropharyngeal swallowing impairment in patients undergoing evaluation for lung transplant"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1693-7311","authenticated-orcid":false,"given":"Kahla","family":"Graham","sequence":"first","affiliation":[{"name":"Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, School of Communication Northwestern University  Evanston Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin L.","family":"Reedy","sequence":"additional","affiliation":[{"name":"Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, School of Communication Northwestern University  Evanston Illinois USA"},{"name":"Edward J. 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