{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T07:40:11Z","timestamp":1755848411169,"version":"3.44.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T00:00:00Z","timestamp":1728172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cyclic vomiting syndrome (CVS), a disorder of gut\u2013brain interaction, presents with recurrent episodes of severe nausea and vomiting. It is often associated with missed or delayed diagnoses and substantial healthcare utilization. Despite historical recognition dating back to the 19th century, epidemiological insights remain limited, with research predominantly originating from specific regions, such as the US. CVS prevalence and incidence rates vary widely and are hindered by inconsistent methodologies and disease recognition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This review aims to provide a comprehensive overview of CVS prevalence and incidence rates. It reviews the currently available data and identifies gaps in knowledge. Understanding the global epidemiology of CVS, increasing awareness of the disease, and fostering global collaboration are crucial. Other pertinent issues include disparities in outcomes, particularly among African Americans and Hispanics in the United States, underscoring the need to understand the social determinants of health that drive disease outcomes. This understanding can inform targeted interventions to address these barriers and achieve equitable healthcare both in the United States and globally.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.14932","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:34:11Z","timestamp":1728261251000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exploring cyclic vomiting syndrome (<scp>CVS<\/scp>) worldwide: Current epidemiological insights and recent developments"],"prefix":"10.1111","volume":"37","author":[{"given":"Rosita","family":"Frazier","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic Arizona  Scottsdale Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0221-8495","authenticated-orcid":false,"given":"Uday C.","family":"Ghoshal","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-9659","authenticated-orcid":false,"given":"Jose","family":"Remes\u2010Troche","sequence":"additional","affiliation":[{"name":"Digestive Physiology and Motility Lab Veracruzana University  Xalapa Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dover","family":"Robin","sequence":"additional","affiliation":[{"name":"Cyclical Vomiting Syndrome Association  Letchworth UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emoto","family":"Shun","sequence":"additional","affiliation":[{"name":"Department of Family Nursing, Division of Health Sciences and Nursing, Graduate School of Medicine The University of Tokyo  Tokyo 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