{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:11:16Z","timestamp":1787753476201,"version":"build-2784847793"},"reference-count":54,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is a bidirectional relationship between sleep and pain disturbances. Sleep disturbances increase the risk for chronic pain, while chronic pain can interfere with sleep. Hence, we assessed the subjective sleep characteristics of youth with functional abdominal pain disorders (FAPDs) compared to healthy youth and examined associations with gastrointestinal symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included youth ages 10\u201318\u2009years without a sleep or organic GI disorder diagnosis from a large private school. Participants completed demographics, sleep history, and validated questionnaires: sleep quality (ASWS\u2010SF), insomnia (PISI), daytime sleepiness (ESS), sleep disturbance (PROMIS SD), sleep\u2010related impairment (PROMIS SRI), and Rome 4 diagnostic questionnaire. Cases (FAPDs) completed abdominal pain index (API), nausea severity (NSS), anxiety, depression (PROMIS), and functional disability (FDI). Parents filled sleep hygiene metrics (SHIP). Cases were matched 1:1 with controls based on age and gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 120 youth (60 cases and 60 controls), the mean age was 13.5\u2009\u00b1\u20091.9\u2009years and 50% were females. Youth with FAPDs had higher insomnia, sleep disturbance, sleep\u2010related impairment, daytime sleepiness, sleep hygiene, gasping, and nightmares than healthy youth (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Higher insomnia severity was associated with worse abdominal pain (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.41,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), higher daytime sleepiness with a family history of disorders of gut\u2010brain interaction (DGBIs, OR\u2009=\u200914.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), and higher sleep\u2010related impairment (OR\u2009=\u20095.6,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02) and depression (OR\u2009=\u20096.1,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) with black race.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Youth with FAPDs have worse sleep than healthy youth and multiple sleep parameters are associated with abdominal pain. Future studies could focus on determining mechanisms by which sleep disturbances affect abdominal pain and vice versa.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.14992","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T07:48:42Z","timestamp":1735631322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Youth With Functional Abdominal Pain Disorders Have More Sleep Disturbances. A School\u2010Based Study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0896-079X","authenticated-orcid":false,"given":"Neha R.","family":"Santucci","sequence":"first","affiliation":[{"name":"Pediatric Gastroenterology Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto","family":"Velasco\u2010Benitez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Universidad del Valle  Cali Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Alejandra","family":"Velasco\u2010Suarez","sequence":"additional","affiliation":[{"name":"Universidad Libre  Cali Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"King","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine and Clinical Psychology Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Byars","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"},{"name":"Division of Behavioral Medicine and Clinical Psychology Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Division of Pulmonary Medicine Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dye","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"},{"name":"Division of Neurology Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Division of Pulmonary \u2013 Sleep Medicine Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Li","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4507-8720","authenticated-orcid":false,"given":"Miguel","family":"Saps","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology, and Nutrition University of Miami School of Medicine  Miami Florida 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