{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:58:24Z","timestamp":1790855904365,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Transanal irrigation is a well\u2010established minimally invasive therapy that addresses symptoms of both constipation and incontinence. The therapy has been extended from just neurogenic bowel dysfunction patients to those with disorders of brain\u2013gut interaction and postsurgical conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To summarized the literature on transanal irrigation and update the contraindication profile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We undertook a literature review of transanal irrigation complications and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Initiation of therapy as part of a bowel care regime is becoming more common outside specialist centers. In addition, the concept of both high\u2010 and low\u2010volume irrigation schedules has entered the treatment paradigm, and it is clear that there is a differing safety profile. We present an update from the previous long list of contraindications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>We describe how optimizing long\u2010term adherence depends on these factors in addition to a structured follow\u2010up programme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Transanal irrigation is an increasingly used therapy, with a good safety profile, further improved by the advent of low\u2010volume irrigation options. Key to safe and effective usage of transanal irrigation is careful patient selection allied to tailored initial training of the patient.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.15011","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T10:56:56Z","timestamp":1737629816000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Consensus on Safe Initiation and Monitoring of Transanal Irrigation to Optimize Adherence With Therapy"],"prefix":"10.1111","volume":"37","author":[{"given":"Anton","family":"Emmanuel","sequence":"first","affiliation":[{"name":"University College Hospital London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Krogh","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Gastroenterology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Perrouin\u2010Verbe","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes Service Universitaire De M\u00e9decine Physique Et R\u00e9adaptation Neurologique  Nantes France"},{"name":"Nantes Universit\u00e9, CHU Nantes, INSERM The Enteric Nervous System in Gut and Brain Disorders  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Krassiukov","sequence":"additional","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), Division of Physical Medicine and Rehabilitation, Department of Medicine University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacha","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Maastricht  Maastricht AZ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Mosiello","sequence":"additional","affiliation":[{"name":"Ospedale Pediatrico Bambino Ges\u00f9  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Bazzocchi","sequence":"additional","affiliation":[{"name":"Montecatone Rehabilitation Institute University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Christensen","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit, Department of Surgery Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianna","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation, Spinal Cord Injury Medicine University of Michigan Health  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concetta","family":"Brugaletta","sequence":"additional","affiliation":[{"name":"University College Hospital London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.06.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2013.86"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181979341"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2023.02.010"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151\u2010023\u201002800\u20107"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16628"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245453"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.20529.1"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12226971"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10081669"},{"key":"e_1_2_11_12_1","unstructured":"NICE \u201cPeristeen Plus Transanal Irrigation System for Managing Bowel Dysfunction. 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