{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:50:14Z","timestamp":1787169014067,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>While the Patient\u2010Reported Outcomes Measurement Information System (PROMIS) global health scales are frequently used to assess individual quality of life, it has yet to be validated in gastrointestinal cohorts. Based on the Rome Foundation Global Epidemiology Survey, the aim of this study was to conduct the most comprehensive psychometric evaluation of the PROMIS health scales (8\u2010item and revised 4\u2010item) across gastrointestinal and non\u2010gastrointestinal condition cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional survey was conducted in 26 countries. A series of confirmatory factor and reliability analyses were undertaken across gastrointestinal condition groups, that is, Disorders of Gut\u2010Brain Interaction (DGBI) [any DGBI, individual DGBI, and DGBI anatomic region], gastroesophageal reflux disease, chronic constipation, chronic diarrhea, coeliac disease, diverticulitis, inflammatory bowel disease, cancer anywhere in the gastrointestinal tract, and peptic ulcer and a non\u2010gastrointestinal condition group. Convergent validity was also assessed via a series of Pearson's correlation coefficients with PHQ\u20104 (anxiety and depression) and PHQ\u201012 (somatization).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Based on 54,040 participants (50.9% male; mean age 44.33\u2009years) confirmatory factor analysis indicated a poor fit for the original Hays et\u00a0al. 4\u2010item version of the PROMIS global health scale. The briefer version 2\u2010factor 2\u2010item model (the Rome alternate model) yielded acceptable fit across all groups. The Hays 2\u2010factor 2\u2010item model subscales also demonstrated strong convergent, content, and construct validity with original PROMIS global health scale subscales across all groups and DGBI regions and across anxiety, depression, and somatization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions &amp; Inferences<\/jats:title>\n                    <jats:p>The 4\u2010item revised version of the Hays model of the PROMIS global health scale demonstrates stronger psychometric properties compared to the original Hays model. This ultra\u2010brief assessment instrument is a viable tool for assessing quality of life in gastrointestinal and non\u2010gastrointestinal cohorts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.70059","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T14:50:16Z","timestamp":1745506216000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Validation of the\n                    <scp>PROMIS<\/scp>\n                    Global Physical and Mental Health Scale for Gastrointestinal Disorders: A Large\u2010Scale Cross\u2010Sectional Survey"],"prefix":"10.1111","volume":"38","author":[{"given":"Pragalathan","family":"Apputhurai","sequence":"first","affiliation":[{"name":"Department of Health Sciences and Biostatistics School of Health Sciences, Swinburne University of Technology  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olafur S.","family":"Palsson","sequence":"additional","affiliation":[{"name":"Center for Functional GI &amp; Motility Disorders University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3111-0689","authenticated-orcid":false,"given":"Shrikant I.","family":"Bangdiwala","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence and Impact McMaster University  Hamilton Ontario Canada"},{"name":"Population Health Research Institute McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7634-3689","authenticated-orcid":false,"given":"Ami D.","family":"Sperber","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonina","family":"Mikocka\u2010Walus","sequence":"additional","affiliation":[{"name":"School of Psychology, Deakin University  Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8000-1000","authenticated-orcid":false,"given":"Simon R.","family":"Knowles","sequence":"additional","affiliation":[{"name":"Department of Psychological Sciences School of Health Sciences, Swinburne University of Technology  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_13_2_1","volume-title":"Guidance for industry. Patient\u2010Reported Outcome Measures: Use in Medial Product Development to Support Labeling Claims","author":"Food and Drug Administration","year":"2009"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.010"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02183.x"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-009-9496-9"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000258615.42478.55"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41687-017-0003-8"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.04.014"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.50.6.613"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04402.x"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2022.12.009"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20166583"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00038\u2010012\u20100416\u20103"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/00273171.2020.1868965"},{"key":"e_1_2_13_15_1","first-page":"121","volume-title":"Multivariate Data Analysis: Its Approach, Evolution, and Impact","author":"Black W.","year":"2019"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.20199"},{"key":"e_1_2_13_17_1","unstructured":"Health NIo \u201cPatient\u2010Reported Outcomes Measurement Information System (PROMIS) \u201d2023 accessed 17 September 2023 https:\/\/commonfund.nih.gov\/promis\/index."},{"key":"e_1_2_13_18_1","volume-title":"User's Manual for the SF\u201036v2TM Health Survey","author":"Ware J. 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