{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:10:09Z","timestamp":1760832609007,"version":"build-2065373602"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Investigation of an evacuation disorder is often pursued in patients with symptoms of obstructive defecation. High\u2010resolution anorectal manometry (HR\u2010ARM) is a simple, safe, and widely available test to diagnose pelvic floor dysfunction. A more costly and less accessible test is magnetic resonance defecography (MRD). This study aims to quantify the added value of MRD in diagnosing pelvic floor disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>HR\u2010ARM and MRD performed in patients with a diagnosis of constipation between January 1, 2020 and May 15, 2022 at Mayo Clinic were identified using Epic Slicer Dicer. Univariate and multivariate analyses were used to compare findings on MRD in patients with and without abnormal HR\u2010ARM. Categorical variables were compared using the Pearson's chi\u2010square test, and continuous variables were compared using the two\u2010sample <jats:italic>t<\/jats:italic>\u2010test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010six consecutive patients (81.8% female, 94.8% White, ages 19\u201382) who underwent both HR\u2010ARM and MRD were included. The majority had evidence of dyssynergia on HR\u2010ARM (<jats:italic>n<\/jats:italic>\u2009=\u200949, 64.5%). Patients with dyssynergia on HR\u2010ARM were significantly more likely to have prolonged balloon expulsion at both &gt;\u200960 and &gt;\u200930\u2009s (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and incomplete gel expulsion on MRD (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). However, they were not more likely to have a clinically significant rectocele measuring &gt;\u20092\u2009cm (<jats:italic>p<\/jats:italic>\u2009=\u20090.17) or evidence of rectal prolapse (<jats:italic>p<\/jats:italic>\u2009=\u20090.07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Anatomic findings on MRD were similar between patients with and without evidence of dyssynergia identified by HR\u2010ARM. In this retrospective review, simultaneously undergoing MRD in addition to HR\u2010ARM does not appear to provide significant additional diagnostic information to guide therapeutic recommendations. Large prospective studies to evaluate the added value of MRD are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.70131","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:00:11Z","timestamp":1754913611000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of High\u2010Resolution Anorectal Manometry and Magnetic Resonance Defecography in Patients With Obstructive Defecation: Are Both Tests Necessary?"],"prefix":"10.1111","volume":"37","author":[{"given":"Haily","family":"Vora","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic in Florida  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4121-7970","authenticated-orcid":false,"given":"Brian","family":"Lacy","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic in Florida  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.12.034"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2022.08.034"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm23066"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14137"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-020-00793-z"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001507"},{"issue":"1","key":"e_1_2_9_8_1","first-page":"28","article-title":"High Resolution Anorectal Manometry in Patients With Anorectal Dysfunctions and the Therapeutic Consequences","volume":"101","author":"Ko\u0161\u0165\u00e1lov\u00e1 K.","year":"2022","journal-title":"Rozhledy v Chirurgii"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13597"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.09.154"},{"key":"e_1_2_9_11_1","article-title":"Patient Online Services \u2010 Patient Estimates","author":"Mayo Clinic","year":"2025","journal-title":"Patient Estimates"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15039"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-018-1759-4"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.03.035"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13679"},{"issue":"3","key":"e_1_2_9_16_1","first-page":"177","article-title":"Normative Values of the Balloon Expulsion Test in Healthy Adults","volume":"18","author":"Dedeli O.","year":"2007","journal-title":"Turkish Journal of Gastroenterology"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2003.10.044"},{"issue":"3","key":"e_1_2_9_18_1","first-page":"469","article-title":"How Useful Are Manometric Tests of Anorectal Function in the Management of Defecation Disorders?","volume":"92","author":"Rao S. S.","year":"1997","journal-title":"American Journal of Gastroenterology"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.01.017"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2013.11.013"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14453"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13314"}],"container-title":["Neurogastroenterology &amp; Motility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nmo.70131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T04:04:16Z","timestamp":1760760256000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nmo.70131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,11]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/nmo.70131"],"URL":"https:\/\/doi.org\/10.1111\/nmo.70131","archive":["Portico"],"relation":{},"ISSN":["1350-1925","1365-2982"],"issn-type":[{"type":"print","value":"1350-1925"},{"type":"electronic","value":"1365-2982"}],"subject":[],"published":{"date-parts":[[2025,8,11]]},"assertion":[{"value":"2024-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70131"}}