{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:10:14Z","timestamp":1760832614475,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The duodenal digestive phase shows irregular non\u2010propagating pressure contractions on antroduodenal manometry (ADM). This study aims to characterize a specific duodenal wave during this phase using high\u2010resolution ADM (HR\u2010ADM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty HR\u2010ADM traces were analyzed. Duodenal waves were identified during meal ingestion and postprandially and assessed for: peaks\/min, mean amplitude, area under the curve (AUC), frequency, propagation length, and velocity. Wave parameters and characteristics are described and compared according to patient symptomatology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>Median patient age was 16\u2009years (range 4\u201319), with 70% female. A total of 292 duodenal waves were identified: 142 during the meal and 150 postprandially. Wave parameter and characteristics by phase were: meal (4.4\u2009\u00b1\u20091.3 peaks\/min, mean amplitude 30.9\u2009\u00b1\u20095.9\u2009mmHg, AUC 295\u2009\u00b1\u200998.2\u2009mmHg*s, frequency 0.23\u2009\u00b1\u20090.1 waves\/min, 15.7\u2009\u00b1\u20094.4\u2009cm propagation length, 1.6\u2009\u00b1\u20091.2\u2009cm\/s velocity) and postprandial (3.8\u2009\u00b1\u20091.3 peaks\/min, mean amplitude 32\u2009\u00b1\u20096.4\u2009mmHg, AUC 245.9\u2009\u00b1\u200976.2\u2009mmHg*s, frequency 0.12\u2009\u00b1\u20090.07 waves\/min, 17.4\u2009\u00b1\u20094.5\u2009cm propagation length, 1.5\u2009\u00b1\u20090.2\u2009cm\/s velocity). All waves had antegrade propagation and were interspersed with semental non\u2010propagating contractions. The wave AUC (<jats:italic>p<\/jats:italic>\u2009=\u20090.008) and frequency (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) were significantly higher during the meal, while propagating length was longer postprandially (<jats:italic>p<\/jats:italic>\u2009=\u20090.009) on paired sample analysis. The wave frequency (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and AUC (<jats:italic>p<\/jats:italic>\u2009=\u20090.043) were significantly higher during the meal on independent sample analysis. No significant difference was found on the rest of the parameters or according to symptom type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and Inferences<\/jats:title><jats:p>This study describes an antegrade propagating duodenal wave during the digestive phase, which may facilitate nutrient movement to the distal small bowel.<\/jats:p><\/jats:sec>","DOI":"10.1111\/nmo.70152","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T10:10:27Z","timestamp":1756807827000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterization of a Duodenal Propagating Wave Identified on High\u2010Resolution Antroduodenal Manometry During the Digestive Phase"],"prefix":"10.1111","volume":"37","author":[{"given":"Ricardo A.","family":"Arbizu","sequence":"first","affiliation":[{"name":"Neurogastroenterology and Motility Center, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Yale New Haven Children's Hospital Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose M.","family":"Garza","sequence":"additional","affiliation":[{"name":"Children's Center for Digestive Health Care Children's Healthcare of Atlanta  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikhianosen","family":"Ukhuedoba","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Yale New Haven Children's Hospital Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariana","family":"Prezzie\u2010Blue","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Yale New Haven Children's Hospital Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Srouji","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Yale New Haven Children's Hospital Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7128-6048","authenticated-orcid":false,"given":"Leonel","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Yale New Haven Children's Hospital Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.280.3.G501"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529708996518"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00091.2004"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003599"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00209.2021"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13239"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003956"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2012.57"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.33549\/physiolres.930000.51.541"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00230.2014"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(84)90080-5"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(86)90878-4"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02064192"},{"key":"e_1_2_10_15_1","first-page":"G423","article-title":"Spatial and Temporal Patterns of Human Jejunal Contractions","volume":"257","author":"Sarna S. 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