{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T12:51:13Z","timestamp":1764507073373,"version":"3.46.0"},"reference-count":44,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100014565","name":"Bausch Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014565","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010721","name":"Ironwood Pharmaceuticals, Incorporated","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010721","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>During the COVID\u201019 pandemic, the prevalence of disorders of gut\u2013brain interaction (DGBI) in the US increased. The pandemic also led to health inequities among racial and ethnic minorities. Here, we conducted monthly national surveys during the pandemic to examine the association between race\/ethnicity and pandemic\u2010onset DGBI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From March 2021 to May 2022, we recruited a nationally representative sample of adults in the US to complete an online survey with Rome IV questionnaires (9 gastroduodenal and bowel DGBI) along with demographic and comorbidity questions. Participants with a DGBI were asked whether their cardinal symptoms started before or after the COVID\u201019 pandemic began in the US (March 2020). Our primary outcome was the prevalence of pandemic\u2010onset DGBI. Multivariable logistic regression models identified factors associated with pandemic\u2010onset DGBI. We also tested for an interaction between race\/ethnicity and COVID\u201019 positivity to assess whether the relationship between pandemic\u2010onset DGBI and race\/ethnicity varied by COVID\u201019 status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 71,547 respondents, 26,103 (36.5%) had \u2265\u20091 DGBI. Across most DGBI, non\u2010Hispanic Blacks and Hispanics had higher odds for pandemic\u2010onset DGBI (e.g., irritable bowel syndrome, functional dyspepsia, functional bloating) versus non\u2010Hispanic Whites. When including interaction terms between race\/ethnicity and COVID\u201019 positivity, most were not significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05), showing that the relationship between pandemic\u2010onset DGBIs and race\/ethnicity did not vary by COVID\u201019 status.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this US survey, racial\/ethnic minorities had higher odds of reporting pandemic\u2010onset DGBI. This association was independent of COVID\u201019 positivity, suggesting that differences in pandemic\u2010onset DGBI among groups may be related to psychosocial challenges faced by racial\/ethnic minorities rather than direct effects of SARS\u2010CoV\u20102.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.70200","type":"journal-article","created":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T04:25:24Z","timestamp":1762575924000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Racial and Ethnic Disparities in Pandemic\u2010Onset Disorders of Gut\u2013Brain Interaction: Results From a Nationwide Survey"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9549-2278","authenticated-orcid":false,"given":"Yixin","family":"Yang","sequence":"first","affiliation":[{"name":"Cedars\u2010Sinai Center for Outcomes Research and Education (CS\u2010CORE)  Los Angeles California USA"},{"name":"Department of Health Policy and Management UCLA Fielding School of Public Health  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brennan M. R.","family":"Spiegel","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Center for Outcomes Research and Education (CS\u2010CORE)  Los Angeles California USA"},{"name":"Department of Health Policy and Management UCLA Fielding School of Public Health  Los Angeles California USA"},{"name":"Karsh Division of Gastroenterology and Hepatology Cedars\u2010Sinai  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Chey","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Michigan Medicine  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So Yung","family":"Choi","sequence":"additional","affiliation":[{"name":"Biostatistics Shared Resource Cedars\u2010Sinai Cancer  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0664-9479","authenticated-orcid":false,"given":"Christopher V.","family":"Almario","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Center for Outcomes Research and Education (CS\u2010CORE)  Los Angeles California USA"},{"name":"Karsh Division of Gastroenterology and Hepatology Cedars\u2010Sinai  Los Angeles California 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